Literature DB >> 9618731

Should we aim at tissue renin-angiotensin systems?

J F Smits1, R C Passier, M J Daemen.   

Abstract

Recent developments in our knowledge of the renin-angiotensin system (RAS) necessitate an update of the classical view on this system. These developments pertain to the pathways leading to formation of angiotensin II and other active metabolites, their receptors, biological functions and the presence of renin-angiotensin systems in tissues. The implications of the above new developments for the current interest in tissue renin-angiotensin systems as potential targets for drug therapy in cardiovascular disease are discussed in this review.

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Year:  1998        PMID: 9618731     DOI: 10.1023/a:1008621913932

Source DB:  PubMed          Journal:  Pharm World Sci        ISSN: 0928-1231


  79 in total

1.  Angiotensin II-stimulated protein synthesis in cultured vascular smooth muscle cells.

Authors:  B C Berk; V Vekshtein; H M Gordon; T Tsuda
Journal:  Hypertension       Date:  1989-04       Impact factor: 10.190

Review 2.  Regression of myocardial and coronary vascular hypertrophy in hypertensive heart disease.

Authors:  B E Strauer
Journal:  J Cardiovasc Pharmacol       Date:  1988       Impact factor: 3.105

3.  Angiotensinogen polymorphism M235T, hypertension, and nephropathy in insulin-dependent diabetes.

Authors:  A Doria; T Onuma; G Gearin; M B Freire; J H Warram; A S Krolewski
Journal:  Hypertension       Date:  1996-05       Impact factor: 10.190

4.  The Renin-Angiotensin and fibrinolytic systems co-conspirators in the pathogenesis of ischemic cardiovascular disease.

Authors:  N J Brown; D E Vaughan
Journal:  Trends Cardiovasc Med       Date:  1996-10       Impact factor: 6.677

5.  Increased accumulation of tissue ACE in human atherosclerotic coronary artery disease.

Authors:  F Diet; R E Pratt; G J Berry; N Momose; G H Gibbons; V J Dzau
Journal:  Circulation       Date:  1996-12-01       Impact factor: 29.690

6.  Angiotensin II is mitogenic in neonatal rat cardiac fibroblasts.

Authors:  W Schorb; G W Booz; D E Dostal; K M Conrad; K C Chang; K M Baker
Journal:  Circ Res       Date:  1993-06       Impact factor: 17.367

7.  Induction of immediate-early genes by angiotensin II and endothelin-1 in adult rat cardiomyocytes.

Authors:  L Neyses; J Nouskas; J Luyken; S Fronhoffs; S Oberdorf; U Pfeifer; R S Williams; V P Sukhatme; H Vetter
Journal:  J Hypertens       Date:  1993-09       Impact factor: 4.844

8.  Receptor-mediated effects of angiotensin II on growth of vascular smooth muscle cells from spontaneously hypertensive rats.

Authors:  B Bunkenburg; T van Amelsvoort; H Rogg; J M Wood
Journal:  Hypertension       Date:  1992-12       Impact factor: 10.190

9.  Characterization of a functional angiotensin IV receptor on coronary microvascular endothelial cells.

Authors:  K L Hall; S Venkateswaran; J M Hanesworth; M E Schelling; J W Harding
Journal:  Regul Pept       Date:  1995-08-22

10.  Metabolism of angiotensin I by different tissues in the intact animal.

Authors:  A H Danser; M M Koning; P J Admiraal; F H Derkx; P D Verdouw; M A Schalekamp
Journal:  Am J Physiol       Date:  1992-08
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