Literature DB >> 9614343

Immune evasion by cytomegalovirus--survival strategies of a highly adapted opportunist.

H Hengel1, W Brune, U H Koszinowski.   

Abstract

Slowly replicating, species-specific and complex DNA viruses, such as cytomegaloviruses (CMVs), which code for > 200 antigenic proteins, should be easy prey to the host's immune system. Yet, CMVs are amazingly adapted opportunists that cope with multiple immune responses. Frequently, CMVs exploit immune mechanisms generated by the host. These strategies secure the persistence of CMVs and provide opportunities to spread to naive individuals.

Mesh：

Year:  1998        PMID： 9614343     DOI： 10.1016/s0966-842x(98)01255-4

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  83 in total

1.  A cytomegalovirus glycoprotein re-routes MHC class I complexes to lysosomes for degradation.

Authors:  U Reusch; W Muranyi; P Lucin; H G Burgert; H Hengel; U H Koszinowski
Journal:  EMBO J       Date:  1999-02-15       Impact factor: 11.598

2.  Macrophages escape inhibition of major histocompatibility complex class I-dependent antigen presentation by cytomegalovirus.

Authors:  H Hengel; U Reusch; G Geginat; R Holtappels; T Ruppert; E Hellebrand; U H Koszinowski
Journal:  J Virol       Date:  2000-09       Impact factor: 5.103

3.  Experimental preemptive immunotherapy of murine cytomegalovirus disease with CD8 T-cell lines specific for ppM83 and pM84, the two homologs of human cytomegalovirus tegument protein ppUL83 (pp65).

Authors:  R Holtappels; J Podlech; N K Grzimek; D Thomas; M F Pahl-Seibert; M J Reddehase
Journal:  J Virol       Date:  2001-07       Impact factor: 5.103

4.  Two antigenic peptides from genes m123 and m164 of murine cytomegalovirus quantitatively dominate CD8 T-cell memory in the H-2d haplotype.

Authors:  Rafaela Holtappels; Doris Thomas; Jürgen Podlech; Matthias J Reddehase
Journal:  J Virol       Date:  2002-01       Impact factor: 5.103

5.  Fast screening procedures for random transposon libraries of cloned herpesvirus genomes: mutational analysis of human cytomegalovirus envelope glycoprotein genes.

Authors:  U Hobom; W Brune; M Messerle; G Hahn; U H Koszinowski
Journal:  J Virol       Date:  2000-09       Impact factor: 5.103

6.  Enrichment of immediate-early 1 (m123/pp89) peptide-specific CD8 T cells in a pulmonary CD62L(lo) memory-effector cell pool during latent murine cytomegalovirus infection of the lungs.

Authors:  R Holtappels; M F Pahl-Seibert; D Thomas; M J Reddehase
Journal:  J Virol       Date:  2000-12       Impact factor: 5.103

Review 7.  Is HCMV a tumor promoter?

Authors:  Liliana Soroceanu; Charles S Cobbs
Journal:  Virus Res       Date:  2010-10-29       Impact factor: 3.303

8.  Loss of linkage disequilibrium and accelerated protein divergence in duplicated cytomegalovirus chemokine genes.

Authors:  Ravit Arav-Boger; Jian-Chao Zong; Charles B Foster
Journal:  Virus Genes       Date:  2005-08       Impact factor: 2.332

9.  Identification and expression of human cytomegalovirus transcription units coding for two distinct Fcgamma receptor homologs.

Authors:  Ramazan Atalay; Albert Zimmermann; Markus Wagner; Eva Borst; Christine Benz; Martin Messerle; Hartmut Hengel
Journal:  J Virol       Date:  2002-09       Impact factor: 5.103

10.  Immune evasion proteins of murine cytomegalovirus preferentially affect cell surface display of recently generated peptide presentation complexes.

Authors:  Niels A W Lemmermann; Kerstin Gergely; Verena Böhm; Petra Deegen; Torsten Däubner; Matthias J Reddehase
Journal:  J Virol       Date:  2009-11-11       Impact factor: 5.103
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