Literature DB >> 9613834

Antihepatotoxic activity of monomethyl fumarate isolated from Fumaria indica.

K S Rao1, S H Mishra.   

Abstract

Monomethyl fumarate, isolated for the first time from the methanolic extract of the whole plant of Fumaria indica, was characterised and screened for its antihepatotoxic activity in albino rats. The compound showed significant (P < 0.01) antihepatotoxic activity against thioacetamide in vitro, and against hepatotoxicities induced by carbon tetrachloride, paracetamol and rifampicin in vivo to an extent almost similar to that of silymarin, a known antihepatotoxic agent.

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Year:  1998        PMID: 9613834     DOI: 10.1016/s0378-8741(97)00149-9

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN: 0378-8741            Impact factor:   4.360


  11 in total

1.  Gastro-protective and Anti-stress Efficacies of Monomethyl Fumarate and a Fumaria indica Extract in Chronically Stressed Rats.

Authors:  Anshul Shakya; Upendra Kumar Soni; Geeta Rai; Shyam Sunder Chatterjee; Vikas Kumar
Journal:  Cell Mol Neurobiol       Date:  2015-07-28       Impact factor: 5.046

Review 2.  A review on ethnobotany, phytochemistry and pharmacology of Fumaria indica (Fumitory).

Authors:  Prakash Chandra Gupta; Nisha Sharma; Ch V Rao
Journal:  Asian Pac J Trop Biomed       Date:  2012-08

3.  Protective effect of stem bark of Ceiba pentandra linn. against paracetamol-induced hepatotoxicity in rats.

Authors:  Nirmal K Bairwa; Neeraj K Sethiya; S H Mishra
Journal:  Pharmacognosy Res       Date:  2010-01

4.  Role of fumaric acid in anti-inflammatory and analgesic activities of a Fumaria indica extracts.

Authors:  Anshul Shakya; Gireesh Kumar Singh; Shyam Sunder Chatterjee; Vikas Kumar
Journal:  J Intercult Ethnopharmacol       Date:  2014-09-22

5.  Effects of Fumaria parviflora leaves extract on reproductive parameters in adult male rats.

Authors:  Mehran Dorostghoal; Seyyed Mansoor Seyyednejad; Lotfollah Khajehpour; Ayoob Jabari
Journal:  Iran J Reprod Med       Date:  2013-11

6.  New phytoconstituents from the aerial parts of Fumaria parviflora Lam.

Authors:  Mohammad Jameel; Abuzer Ali; Mohammed Ali
Journal:  J Adv Pharm Technol Res       Date:  2014-04

7.  Protective effect of extracts of Baliospermum montanum (Willd.) Muell.-Arg. against paracetamol-induced hepatotoxicity-an in vivo and in vitro study.

Authors:  S V Suresh Kumar; S H Mishra
Journal:  Anc Sci Life       Date:  2014 Apr-Jun

8.  Potential antianxiety activity of Fumaria indica: A preclinical study.

Authors:  Gireesh K Singh; Sudhir K Chauhan; Geeta Rai; Shyam S Chatterjee; Vikas Kumar
Journal:  Pharmacogn Mag       Date:  2013-01       Impact factor: 1.085

9.  Effects of ethanolic extract of Fumaria indica L. on rat cognitive dysfunctions.

Authors:  Gireesh Kumar Singh; Geeta Rai; Shyam Sunder Chatterjee; Vikas Kumar
Journal:  Ayu       Date:  2013-10

10.  Antiulcer activity of Amlapitta Mishran suspension in rats: A pilot study.

Authors:  Sampath K Vemula; Mukesh B Chawada; Kapil S Thakur; Mahesh K Vahalia
Journal:  Anc Sci Life       Date:  2012-10
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