Literature DB >> 9613340

Quality control of synovial fluid crystal identification.

R von Essen1, A M Hölttä, R Pikkarainen.   

Abstract

OBJECTIVE: To establish a quality assessment programme for the diagnosis of crystal arthropathies by synovial fluid (SF) microscopy.
METHODS: Three or four cytocentrifuge slides prepared from suitable patient SF specimens were distributed to 25-47 predominantly Finnish clinical laboratories once a year. Sodium urate crystals were included in every survey.
RESULTS: Returns for the years 1989-1996 were reviewed. Laboratories that participated in > four surveys made on an average one error a year (range 0.25-2). The error rate for specimens containing abundant crystals was acceptable but it increased considerably for specimens showing few crystals per microscope field. No laboratory characteristic predictive of successful performance was found.
CONCLUSION: Errors in quality assessment results for crystal identification were much more frequent than in the fields of, for example, clinical chemistry or microbiology. Despite efforts to provide educational feedback, no improvement was seen during the study period. Because of the dearth of data from other parts of the world it is not known for certain whether this study has merely pinpointed a local problem or if the same trend applies elsewhere.

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Year:  1998        PMID: 9613340      PMCID: PMC1752532          DOI: 10.1136/ard.57.2.107

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN: 0003-4967            Impact factor:   19.103


  17 in total

Review 1.  Identification of crystals in synovial fluids and joint tissues.

Authors:  A K Rosenthal; N Mandel
Journal:  Curr Rheumatol Rep       Date:  2001-02       Impact factor: 4.592

2.  Crystal arthritis: calcium pyrophosphate deposition-nothing 'pseudo' about it!

Authors:  Ann K Rosenthal; Lawrence M Ryan
Journal:  Nat Rev Rheumatol       Date:  2011-05       Impact factor: 20.543

3.  The cytospin technique improves the detection of calcium pyrophosphate crystals in synovial fluid samples with a low leukocyte count.

Authors:  Christoph Robier; Franz Quehenberger; Manfred Neubauer; Mariana Stettin; Franz Rainer
Journal:  Rheumatol Int       Date:  2013-02-07       Impact factor: 2.631

4.  Analysis for crystals in synovial fluid: training of the analysts results in high consistency.

Authors:  B Lumbreras; E Pascual; J Frasquet; J González-Salinas; E Rodríguez; I Hernández-Aguado
Journal:  Ann Rheum Dis       Date:  2005-04       Impact factor: 19.103

5.  Crystal identification of synovial fluid aspiration by polarized light microscopy. An online test suggesting that our traditional rheumatologic competence needs renewed attention and training.

Authors:  D Berendsen; T Neogi; W J Taylor; N Dalbeth; T L Jansen
Journal:  Clin Rheumatol       Date:  2016-11-11       Impact factor: 2.980

6.  Delayed examination of synovial fluid by ordinary and polarised light microscopy to detect and identify crystals.

Authors:  J Gálvez; E Sáiz; L F Linares; A Climent; C Marras; M F Pina; P Castellón
Journal:  Ann Rheum Dis       Date:  2002-05       Impact factor: 19.103

Review 7.  Crystal-induced inflammation and cartilage degradation.

Authors:  G M McCarthy
Journal:  Curr Rheumatol Rep       Date:  1999-12       Impact factor: 4.592

8.  Cytospin preparations are superior to common smears in the detection of monosodium urate crystals in low-cellular synovial fluids.

Authors:  Christoph Robier; Mariana Stettin; Franz Quehenberger; Manfred Neubauer
Journal:  Clin Rheumatol       Date:  2014-04-18       Impact factor: 2.980

9.  The detection of calcium pyrophosphate crystals in the synovial fluid of patients with rheumatoid arthritis using the cytospin technique: prevalence and clinical correlation.

Authors:  Georg Theiler; Franz Quehenberger; Franz Rainer; Manfred Neubauer; Mariana Stettin; Christoph Robier
Journal:  Rheumatol Int       Date:  2012-12-27       Impact factor: 2.631

Review 10.  Detection of calcium phosphate crystals in the joint fluid of patients with osteoarthritis - analytical approaches and challenges.

Authors:  Alexander Yavorskyy; Aaron Hernandez-Santana; Geraldine McCarthy; Gillian McMahon
Journal:  Analyst       Date:  2008-02-01       Impact factor: 4.616

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