Literature DB >> 9611094

Detailed characterization of the 1087 MeV/nucleon iron-56 beam used for radiobiology at the alternating gradient synchrotron.

C Zeitlin1, L Heilbronn, J Miller.   

Abstract

We report beam characterization and dosimetric measurements made using a 56Fe beam extracted from the Brookhaven National Laboratory Alternating Gradient Synchrotron (AGS) with a kinetic energy of 1087 MeV/nucleon. The measurements reveal that the depth-dose distribution of this beam differs significantly from that obtained with a 600 MeV/nucleon iron beam used in several earlier radiobiology experiments at the Lawrence Berkeley National Laboratory's BEVALAC. We present detailed measurements of beam parameters relevant for radiobiology, including track- and dose-averaged linear energy transfer (LET), fragment composition and LET spectra measured behind sample holders used in irradiations of biological samples. We also report measurements of fluence behind three depths (1.94, 4.68 and 9.35 g cm(-2)) of polyethylene targets with the 1087 MeV/nucleon beam, and behind 1.94 g cm(-2) of polyethylene with a 610 MeV/nucleon beam delivered by the AGS. These results are compared to earlier measurements with the 600 MeV/nucleon beam at the BEVALAC.

Entities:  

Keywords:  NASA Discipline Radiation Health; Non-NASA Center

Mesh:

Substances:

Year:  1998        PMID: 9611094

Source DB:  PubMed          Journal:  Radiat Res        ISSN: 0033-7587            Impact factor:   2.841


  11 in total

1.  Clustered DNA damages induced in isolated DNA and in human cells by low doses of ionizing radiation.

Authors:  B M Sutherland; P V Bennett; O Sidorkina; J Laval
Journal:  Proc Natl Acad Sci U S A       Date:  2000-01-04       Impact factor: 11.205

2.  Trauma-induced alterations in cognition and Arc expression are reduced by previous exposure to 56Fe irradiation.

Authors:  Susanna Rosi; Karim Belarbi; Ryan A Ferguson; Kelly Fishman; Andre Obenaus; Jacob Raber; John R Fike
Journal:  Hippocampus       Date:  2010-12-29       Impact factor: 3.899

3.  Hippocampal neurogenesis and neuroinflammation after cranial irradiation with (56)Fe particles.

Authors:  Radoslaw Rola; Kelly Fishman; Jennifer Baure; Susanna Rosi; Kathleen R Lamborn; Andre Obenaus; Gregory A Nelson; John R Fike
Journal:  Radiat Res       Date:  2008-06       Impact factor: 2.841

4.  Low level irradiation in mice can lead to enhanced trabecular bone morphology.

Authors:  Lamya Karim; Stefan Judex
Journal:  J Bone Miner Metab       Date:  2013-10-11       Impact factor: 2.626

5.  Germ cell mutagenesis in medaka fish after exposures to high-energy cosmic ray nuclei: A human model.

Authors:  Atsuko Shimada; Akihiro Shima; Kumie Nojima; Yo Seino; Richard B Setlow
Journal:  Proc Natl Acad Sci U S A       Date:  2005-04-13       Impact factor: 11.205

6.  Effect of diet on the disruption of operant responding at different ages following exposure to (56)Fe particles.

Authors:  Bernard M Rabin; Kirsty L Carrihill-Knoll; Amanda Carey; Barbara Shukitt-Hale; James A Joseph
Journal:  Age (Dordr)       Date:  2005-05-02

7.  WR-1065, the active metabolite of amifostine, mitigates radiation-induced delayed genomic instability.

Authors:  Jaroslaw Dziegielewski; Janet E Baulch; Wilfried Goetz; Mitchell C Coleman; Douglas R Spitz; Jeffrey S Murley; David J Grdina; William F Morgan
Journal:  Free Radic Biol Med       Date:  2008-09-18       Impact factor: 7.376

8.  Chromosome damage in human cells by γ rays, α particles and heavy ions: track interactions in basic dose-response relationships.

Authors:  Bradford D Loucas; Marco Durante; Susan M Bailey; Michael N Cornforth
Journal:  Radiat Res       Date:  2012-11-30       Impact factor: 2.841

9.  Shielding of relativistic protons.

Authors:  A Bertucci; M Durante; G Gialanella; G Grossi; L Manti; M Pugliese; P Scampoli; D Mancusi; L Sihver; A Rusek
Journal:  Radiat Environ Biophys       Date:  2007-01-26       Impact factor: 2.017

10.  Redox changes induced in hippocampal precursor cells by heavy ion irradiation.

Authors:  C L Limoli; E Giedzinski; J Baure; R Rola; J R Fike
Journal:  Radiat Environ Biophys       Date:  2006-11-14       Impact factor: 2.017

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