BACKGROUND: The lack of a suitable noninvasive method for assessing right ventricular (RV) volume and function has been a major deficiency of two-dimensional (2D) echocardiography. The aim of our animal study was to test a new real-time three-dimensional (3D) echo imaging system for evaluating RV stroke volumes. METHODS AND RESULTS: Three to 6 months before hemodynamic and 3D ultrasonic study, the pulmonary valve was excised from 6 sheep (31 to 59 kg) to induce RV volume overload. At the subsequent session, a total of 14 different steady-state hemodynamic conditions were studied. Electromagnetic (EM) flow probes were used for obtaining aortic and pulmonic flows. A unique phased-array volumetric 3D imaging system developed at the Duke University Center for Emerging Cardiovascular Technology was used for ultrasonic imaging. Real-time volumetric images of the RV were digitally stored, and RV stroke volumes were determined by use of parallel slices of the 3D RV data set and subtraction of end-systolic cavity volumes from end-diastolic cavity volumes. Multiple regression analyses showed a good correlation and agreement between the EM-obtained RV stroke volumes (range, 16 to 42 mL/beat) and those obtained by the new real-time 3D method (r=0.80; mean difference, -2.7+/-6.4 mL/beat). CONCLUSIONS: The real-time 3D system provided good estimation of strictly quantified reference RV stroke volumes, suggesting an important application of this new 3D method.
BACKGROUND: The lack of a suitable noninvasive method for assessing right ventricular (RV) volume and function has been a major deficiency of two-dimensional (2D) echocardiography. The aim of our animal study was to test a new real-time three-dimensional (3D) echo imaging system for evaluating RV stroke volumes. METHODS AND RESULTS: Three to 6 months before hemodynamic and 3D ultrasonic study, the pulmonary valve was excised from 6 sheep (31 to 59 kg) to induce RV volume overload. At the subsequent session, a total of 14 different steady-state hemodynamic conditions were studied. Electromagnetic (EM) flow probes were used for obtaining aortic and pulmonic flows. A unique phased-array volumetric 3D imaging system developed at the Duke University Center for Emerging Cardiovascular Technology was used for ultrasonic imaging. Real-time volumetric images of the RV were digitally stored, and RV stroke volumes were determined by use of parallel slices of the 3D RV data set and subtraction of end-systolic cavity volumes from end-diastolic cavity volumes. Multiple regression analyses showed a good correlation and agreement between the EM-obtained RV stroke volumes (range, 16 to 42 mL/beat) and those obtained by the new real-time 3D method (r=0.80; mean difference, -2.7+/-6.4 mL/beat). CONCLUSIONS: The real-time 3D system provided good estimation of strictly quantified reference RV stroke volumes, suggesting an important application of this new 3D method.
Authors: Ares Pasipoularides; Ming Shu; Ashish Shah; Michael S Womack; Donald D Glower Journal: Am J Physiol Heart Circ Physiol Date: 2003-04 Impact factor: 4.733
Authors: Ares D Pasipoularides; Ming Shu; Michael S Womack; Ashish Shah; Olaf Von Ramm; Donald D Glower Journal: Am J Physiol Heart Circ Physiol Date: 2002-09-12 Impact factor: 4.733
Authors: Hans Jaochim Nesser; Lissa Sugeng; Cristiana Corsi; Lynn Weinert; Johannes Niel; Christian Ebner; Regina Steringer-Mascherbauer; Frank Schmidt; Georg Schummers; Roberto M Lang; Victor Mor-Avi Journal: Heart Date: 2006-09-15 Impact factor: 5.994
Authors: Diego Medvedofsky; Karima Addetia; Jamie Hamilton; Javier Leon Jimenez; Roberto M Lang; Victor Mor-Avi Journal: Int J Cardiovasc Imaging Date: 2015-05-07 Impact factor: 2.357
Authors: T Stan Gregory; John Oshinski; Ehud J Schmidt; Raymond Y Kwong; William G Stevenson; Zion Tsz Ho Tse Journal: Circ Cardiovasc Imaging Date: 2015-12 Impact factor: 7.792
Authors: Jun Kwan; Beom Woo Yeom; Michael Jones; Jian Xin Qin; Arthur D Zetts; James D Thomas; Takahiro Shiota Journal: J Korean Med Sci Date: 2006-04 Impact factor: 2.153