| Literature DB >> 9608661 |
V Suryanarayana1, P Tulasiram, K S Prabhudas, L D Misra, C Natarajan.
Abstract
Vaccination is the only pragmatic approach to control foot and mouth disease in India. Strict quality control measures are essential to supply potent vaccine to the field application, in addition to monitoring the performance of the vaccine in the field. During the process of monitoring, an outbreak of FMD in vaccinated animals caused by type "O" virus in Tanjavur district of Tamil Nadu and a type "O" virus from unvaccinated herd of Karnataka were studied. Field isolates and vaccine virus were sequenced and analyzed. Data indicated that the virus from the outbreak in vaccinated cattle was a variant which could escape neutralization by antibodies against vaccine virus.Entities:
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Year: 1998 PMID: 9608661 DOI: 10.1023/a:1007993606750
Source DB: PubMed Journal: Virus Genes ISSN: 0920-8569 Impact factor: 2.332