Literature DB >> 9608414

A preliminary study of D-cycloserine treatment in Alzheimer's disease.

G E Tsai1, W E Falk, J Gunther.   

Abstract

D-cycloserine is a partial agonist on the glycine site of the N-methyl-D-aspartate glutamate receptor. This double-blind crossover study of 15 mg D-cycloserine in Alzheimer's disease patients did not demonstrate clinical benefit. Higher medication dosage or long-term treatment may be required.

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Year:  1998        PMID： 9608414     DOI： 10.1176/jnp.10.2.224

Source DB:  PubMed          Journal:  J Neuropsychiatry Clin Neurosci        ISSN： 0895-0172            Impact factor:   2.198


  9 in total

Review 1.  Pharmacological treatments that facilitate extinction of fear: relevance to psychotherapy.

Authors:  Michael Davis; Karyn M Myers; Jasmeer Chhatwal; Kerry J Ressler
Journal:  NeuroRx       Date:  2006-01

Review 2.  The role of the N-methyl-D-aspartate receptor in Alzheimer's disease: therapeutic potential.

Authors:  P Murali Doraiswamy
Journal:  Curr Neurol Neurosci Rep       Date:  2003-09       Impact factor: 5.081

Review 3.  D-cycloserine for Alzheimer's disease.

Authors:  K Laake; A R Oeksengaard
Journal:  Cochrane Database Syst Rev       Date:  2002

Review 4.  NMDA receptors in clinical neurology: excitatory times ahead.

Authors:  Lorraine V Kalia; Suneil K Kalia; Michael W Salter
Journal:  Lancet Neurol       Date:  2008-08       Impact factor: 44.182

Review 5.  The Role of N-Methyl-D-Aspartate Receptor Neurotransmission and Precision Medicine in Behavioral and Psychological Symptoms of Dementia.

Authors:  Chieh-Hsin Lin; Hsien-Yuan Lane
Journal:  Front Pharmacol       Date:  2019-05-22       Impact factor: 5.810

Review 6.  Involvement of Cholinergic, Adrenergic, and Glutamatergic Network Modulation with Cognitive Dysfunction in Alzheimer's Disease.

Authors:  Yu-Jung Cheng; Chieh-Hsin Lin; Hsien-Yuan Lane
Journal:  Int J Mol Sci       Date:  2021-02-25       Impact factor: 5.923

7.  Effect of N-methyl-D-aspartate receptor enhancing agents on cognition in dementia: an exploratory systematic review and meta-analysis of randomized controlled trials.

Authors:  Chun-Hung Chang; Chieh-Yu Liu; Shaw-Ji Chen; Hsin-Chi Tsai
Journal:  Sci Rep       Date:  2021-11-26       Impact factor: 4.379

8.  Assessment of the neuroprotective potential of d-cycloserine and l-serine in aluminum chloride-induced experimental models of Alzheimer's disease: In vivo and in vitro studies.

Authors:  Özlem Özdemir Tozlu; Hasan Türkez; Ufuk Okkay; Onur Ceylan; Cemil Bayram; Ahmet Hacımüftüoğlu; Adil Mardinoğlu
Journal:  Front Nutr       Date:  2022-09-08

9.  NMDA Neurotransmission Dysfunction in Behavioral and Psychological Symptoms of Alzheimer's Disease.

Authors:  Yu-Jhen Huang; Chieh-Hsin Lin; Hsien-Yuan Lane; Guochuan E Tsai
Journal:  Curr Neuropharmacol       Date:  2012-09       Impact factor: 7.363
  9 in total

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