Papular acrodermatitis of childhood related to poxvirus and parvovirus B19 infection.

Papular acrodermatitis of childhood (Gianotti-Crosti syndrome) is considered an unspecific cutaneous pattern related to an increasing number of infectious diseases. We report two cases of Gianotti-Crosti syndrome, one of which occurred in the setting of parvovirus B19 primary infection and the other followed poxvirus infection. Parvovirus B19 and poxvirus may represent new causative agents of Gianotti-Crosti syndrome.