Literature DB >> 960793

[Teratogenic and mutagenic studies with caffeine in the animal experiment].

T von Kreybig, G Czok.   

Abstract

Principles of teratogenic and mutagenic actions are defined. The recent experimental studies with laboratory animals, and our investigations with caffeine-sodium benzoicum and with soluble coffee in pregnant rats and mice showed no teratogenicity. The results are compared with specific teratogenic effects of cytostatic agents. A teratogenicity of caffeine can be excluded, a mutagenicity in animal experiments can also not be proved.

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Year:  1976        PMID: 960793     DOI: 10.1007/BF02283139

Source DB:  PubMed          Journal:  Z Ernahrungswiss        ISSN: 0044-264X


  16 in total

Review 1.  Effects of caffeine on the genetic material.

Authors:  B A Kihlman
Journal:  Mutat Res       Date:  1974-04       Impact factor: 2.433

2.  The enhancement by caffeine of alkylation-induced cell death, mutations and chromosomal aberrations in Chinese hamster cells, as a result of inhibition of post-replication DNA repair.

Authors:  J J Roberts; J E Sturrock; K N Ward
Journal:  Mutat Res       Date:  1974-04       Impact factor: 2.433

3.  [Studies on mutagenity in mice after administration of caffeine].

Authors:  G Röhrborn
Journal:  Z Ernahrungswiss Suppl       Date:  1972

4.  Genetic effects of caffeine.

Authors:  N Loprieno; R Barale; S Baroncelli
Journal:  Mutat Res       Date:  1974-04       Impact factor: 2.433

5.  The cytogenetic effects of caffeine on two tumour cell lines.

Authors:  N Bishun; D Williams; J Mills
Journal:  Mutat Res       Date:  1974-04       Impact factor: 2.433

6.  The inhibiting effect of caffeine on the maternal repair of radiation-induced chromosome breaks in Drosophila.

Authors:  D Mendelson; F H Sobels
Journal:  Mutat Res       Date:  1974-04       Impact factor: 2.433

7.  Genetic tests in mice of caffeine alone and in combination with mutagens.

Authors:  P S Thayer; C J Kensler
Journal:  Toxicol Appl Pharmacol       Date:  1973-06       Impact factor: 4.219

8.  [Frequency and sequelae of mutagenic and teratogenic substances].

Authors:  T von Kreybig
Journal:  Verh Dtsch Ges Inn Med       Date:  1973

9.  Adverse effects of prolonged administration of caffeine on rat fetus.

Authors:  T Fujii; H Nishimura
Journal:  Toxicol Appl Pharmacol       Date:  1972-07       Impact factor: 4.219

10.  [Experimental teratogenesis: study of caffeine in mice].

Authors: 
Journal:  Therapie       Date:  1969 Jul-Aug       Impact factor: 2.070

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