Literature DB >> 9603319

Expression of ORF A1 of infectious bursal disease virus results in the formation of virus-like particles.

A Fernández-Arias1, C Risco, S Martínez, J P Albar, J F Rodríguez.   

Abstract

A recombinant vaccinia virus inducibly expressing ORF A1 of infectious bursal disease virus (IBDV) has been constructed and characterized. Cells infected with this recombinant virus express the IBDV polyprotein, which is proteolytically processed to give mature VP2, VP3, and VP4 polypeptides. An electron microscopy study revealed that the cytoplasm of cells infected with the recombinant virus contains abundant IBDV-like particles (VLP). These VLP form close-packed paracrystalline arrays that are specifically recognized by anti-IBDV antibodies. The size and morphology of purified VLP were found to be akin to those of authentic IBDV particles.

Entities:  

Mesh：

Substances：

Year:  1998        PMID： 9603319     DOI： 10.1099/0022-1317-79-5-1047

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  23 in total

1.  Type I Interferon acts as a major barrier to the establishment of infectious bursal disease virus (IBDV) persistent infections.

Authors:  Laura Broto; Nicolás Romero; Fernando Méndez; Elisabet Diaz-Beneitez; Oscar Candelas-Rivera; Daniel Fuentes; Liliana L Cubas-Gaona; Céline Courtillon; Nicolas Eterradossi; Sébastien M Soubies; Juan R Rodríguez; Dolores Rodríguez; José F Rodríguez
Journal:  J Virol       Date:  2020-12-16       Impact factor: 5.103

2.  Infectious bursal disease virus capsid protein VP3 interacts both with VP1, the RNA-dependent RNA polymerase, and with viral double-stranded RNA.

Authors:  Mirriam G J Tacken; Ben P H Peeters; Adri A M Thomas; Peter J M Rottier; Hein J Boot
Journal:  J Virol       Date:  2002-11       Impact factor: 5.103

3.  The endosomal pathway and the Golgi complex are involved in the infectious bursal disease virus life cycle.

Authors:  Laura R Delgui; José F Rodríguez; María I Colombo
Journal:  J Virol       Date:  2013-06-05       Impact factor: 5.103

4.  VP1, the putative RNA-dependent RNA polymerase of infectious bursal disease virus, forms complexes with the capsid protein VP3, leading to efficient encapsidation into virus-like particles.

Authors:  E Lombardo; A Maraver; J R Castón; J Rivera; A Fernández-Arias; A Serrano; J L Carrascosa; J F Rodriguez
Journal:  J Virol       Date:  1999-08       Impact factor: 5.103

5.  Exchange of the C-terminal part of VP3 from very virulent infectious bursal disease virus results in an attenuated virus with a unique antigenic structure.

Authors:  Hein J Boot; A Agnes H M ter Huurne; Arjan J W Hoekman; Jan M Pol; Arno L J Gielkens; Ben P H Peeters
Journal:  J Virol       Date:  2002-10       Impact factor: 5.103

6.  C terminus of infectious bursal disease virus major capsid protein VP2 is involved in definition of the T number for capsid assembly.

Authors:  J R Castón; J L Martínez-Torrecuadrada; A Maraver; E Lombardo; J F Rodríguez; J I Casal; J L Carrascosa
Journal:  J Virol       Date:  2001-11       Impact factor: 5.103

7.  Exacerbated Apoptosis of Cells Infected with Infectious Bursal Disease Virus upon Exposure to Interferon Alpha.

Authors:  Liliana L Cubas-Gaona; Elisabet Diaz-Beneitez; Marina Ciscar; José F Rodríguez; Dolores Rodríguez
Journal:  J Virol       Date:  2018-05-14       Impact factor: 5.103

8.  Infectious Bursal Disease Virus Hijacks Endosomal Membranes as the Scaffolding Structure for Viral Replication.

Authors:  María Cecilia Gimenez; Flavia Adriana Zanetti; Mauricio R Terebiznik; María Isabel Colombo; Laura Ruth Delgui
Journal:  J Virol       Date:  2018-05-14       Impact factor: 5.103

9.  Autoproteolytic activity derived from the infectious bursal disease virus capsid protein.

Authors:  Nerea Irigoyen; Damià Garriga; Aitor Navarro; Nuria Verdaguer; José F Rodríguez; José R Castón
Journal:  J Biol Chem       Date:  2009-01-14       Impact factor: 5.157

10.  The oligomerization domain of VP3, the scaffolding protein of infectious bursal disease virus, plays a critical role in capsid assembly.

Authors:  Antonio Maraver; Ana Oña; Fernando Abaitua; Dolores González; Roberto Clemente; Jose A Ruiz-Díaz; Jose R Castón; Florencio Pazos; Jose F Rodriguez
Journal:  J Virol       Date:  2003-06       Impact factor: 5.103
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.