Literature DB >> 9602301

Reading within the lines: naturally processed peptides displayed by MHC class I molecules.

N Shastri1, T Serwold, P Paz.   

Abstract

A typical mammalian cell contains tens of thousands of different gene products. Snippets of this genetic information are displayed on the cell surface by MHC class I molecules as short peptides for immune surveillance by CD8+ T lymphocytes. Genetic and biochemical analysis of these peptides is revealing novel sources and mechanisms by which these peptide/MHC class I complexes arise.

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Year:  1998        PMID： 9602301     DOI： 10.1016/s0952-7915(98)80241-0

Source DB:  PubMed          Journal:  Curr Opin Immunol        ISSN： 0952-7915            Impact factor:   7.486


  2 in total

1.  The design and implementation of the immune epitope database and analysis resource.

Authors:  Bjoern Peters; John Sidney; Phil Bourne; Huynh-Hoa Bui; Soeren Buus; Grace Doh; Ward Fleri; Mitch Kronenberg; Ralph Kubo; Ole Lund; David Nemazee; Julia V Ponomarenko; Muthu Sathiamurthy; Stephen P Schoenberger; Scott Stewart; Pamela Surko; Scott Way; Steve Wilson; Alessandro Sette
Journal:  Immunogenetics       Date:  2005-05-14       Impact factor: 2.846

2.  ERAAP synergizes with MHC class I molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum.

Authors:  Takayuki Kanaseki; Nicolas Blanchard; Gianna Elena Hammer; Federico Gonzalez; Nilabh Shastri
Journal:  Immunity       Date:  2006-11       Impact factor: 31.745
  2 in total

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