Literature DB >> 9601609

Calcium regulation of basic helix-loop-helix transcription factors.

S Hermann1, J Saarikettu, J Onions, K Hughes, T Grundström.   

Abstract

The basic helix-loop-helix (bHLH) family of transcription factors is essential for numerous developmental and growth control processes. The regulation of bHLH proteins occurs at many levels, including tissue specific expression, differential oligomerization and DNA binding specificities, interaction with negatively acting HLH proteins and post-translational modifications. This review focuses on what is emerging as another level of bHLH protein regulation, calcium regulation through interaction with Ca2+ loaded calmodulin and S-100 proteins. The mechanism and implications of these Ca2+ regulated interactions are discussed.

Entities:  

Mesh：

Substances：

Year:  1998        PMID： 9601609     DOI： 10.1016/s0143-4160(98)90112-9

Source DB:  PubMed          Journal:  Cell Calcium        ISSN： 0143-4160            Impact factor:   6.817


  9 in total

1.  Regulation of c-Rel nuclear localization by binding of Ca2+/calmodulin.

Authors:  Asa Antonsson; Kate Hughes; Sofia Edin; Thomas Grundström
Journal:  Mol Cell Biol       Date:  2003-02       Impact factor: 4.272

Review 2.  Mechanisms of Vascular Smooth Muscle Contraction and the Basis for Pharmacologic Treatment of Smooth Muscle Disorders.

Authors:  F V Brozovich; C J Nicholson; C V Degen; Yuan Z Gao; M Aggarwal; K G Morgan
Journal:  Pharmacol Rev       Date:  2016-04       Impact factor: 25.468

3.  Intrinsically disordered human C/EBP homologous protein regulates biological activity of colon cancer cells during calcium stress.

Authors:  Vinay K Singh; Ivan Pacheco; Vladimir N Uversky; Steven P Smith; R John MacLeod; Zongchao Jia
Journal:  J Mol Biol       Date:  2008-05-03       Impact factor: 5.469

4.  Circadian modulation of calcium levels in cells in the suprachiasmatic nucleus.

Authors:  C S Colwell
Journal:  Eur J Neurosci       Date:  2000-02       Impact factor: 3.386

Review 5.  Calmodulin-driven nuclear entry: trigger for sex determination and terminal differentiation.

Authors:  John A Hanover; Dona C Love; William A Prinz
Journal:  J Biol Chem       Date:  2009-01-05       Impact factor: 5.157

6.  G protein-coupled receptor kinase 5 contains a DNA-binding nuclear localization sequence.

Authors:  Laura R Johnson; Mark G H Scott; Julie A Pitcher
Journal:  Mol Cell Biol       Date:  2004-12       Impact factor: 4.272

7.  Molecular Mechanisms of Transcription Factor 4 in Pitt Hopkins Syndrome.

Authors:  Matthew D Rannals; Brady J Maher
Journal:  Curr Genet Med Rep       Date:  2017-02-11

8.  The calcium: an early signal that initiates the formation of the nervous system during embryogenesis.

Authors:  Catherine Leclerc; Isabelle Néant; Marc Moreau
Journal:  Front Mol Neurosci       Date:  2012-05-14       Impact factor: 5.639

9.  A divalent ion is crucial in the structure and dominant-negative function of ID proteins, a class of helix-loop-helix transcription regulators.

Authors:  Marie Vivian Wong; Sizun Jiang; Paaventhan Palasingam; Prasanna R Kolatkar
Journal:  PLoS One       Date:  2012-10-30       Impact factor: 3.240
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.