| Literature DB >> 9601603 |
O H Petersen1, O V Gerasimenko, J V Gerasimenko, H Mogami, A V Tepikin.
Abstract
The nuclear envelope has a relatively small volume, but is connected up to the vastly larger endoplasmic reticulum. The Ca2+ concentration in the lumen of the interconnected nuclear envelope and endoplasmic reticulum network is in the resting state maintained at a level of more than 100 microM. There are specific Ca2+ release channels present in the inner nuclear membrane that can be activated by inositol trisphosphate or cADP ribose. The system, therefore, allows selective release of Ca2+ into the nucleoplasm which could be important for the control of specific types of gene expression.Entities:
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Year: 1998 PMID： 9601603 DOI： 10.1016/s0143-4160(98)90106-3
Source DB: PubMed Journal: Cell Calcium ISSN： 0143-4160 Impact factor: 6.817