| Literature DB >> 9601013 |
A J Klar1, A V Ivanova, J Z Dalgaard, M J Bonaduce, S I Grewal.
Abstract
Two epigenetic events at mat1, one of which is DNA strand specific, are required to initiate recombination during mating-type switching. The third, a chromosomally borne imprinted event at the mat2/3 interval regulates silencing and directionality of switching, and prohibits interchromosomal recombination. We speculate that the unit of inheritance in the mat2/3 interval is both DNA plus its associated chromatin structure. Such a control is likely to be essential in maintaining particular states of gene expression during development.Entities:
Mesh：
Substances：
Year: 1998 PMID： 9601013 DOI： 10.1002/9780470515501.ch6
Source DB: PubMed Journal: Novartis Found Symp ISSN： 1528-2511