| Literature DB >> 9600981 |
E R Olivera1, B Miñambres, B García, C Muñiz, M A Moreno, A Ferrández, E Díaz, J L García, J M Luengo.
Abstract
Fourteen different genes included in a DNA fragment of 18 kb are involved in the aerobic degradation of phenylacetic acid by Pseudomonas putida U. This catabolic pathway appears to be organized in three contiguous operons that contain the following functional units: (i) a transport system, (ii) a phenylacetic acid activating enzyme, (iii) a ring-hydroxylation complex, (iv) a ring-opening protein, (v) a beta-oxidation-like system, and (vi) two regulatory genes. This pathway constitutes the common part (core) of a complex functional unit (catabolon) integrated by several routes that catalyze the transformation of structurally related molecules into a common intermediate (phenylacetyl-CoA).Entities:
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Year: 1998 PMID: 9600981 PMCID: PMC27761 DOI: 10.1073/pnas.95.11.6419
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205