Literature DB >> 9599411

Adaptation in cyclic AMP signalling processes: a central role for cyclic AMP phosphodiesterases.

M D Houslay1.   

Abstract

Cyclic AMP has provided the paradigm for the second messenger concept. Recent evidence has identified a complex array of isoforms of the enzymes involved in generation, destroying and transmitting the effects of this second messenger. These proteins provide a sophisticated system for organising cAMP signal transduction in specific intracellular compartments; for allowing integration with other signalling systems and for controlling the kinetics and hence reaction characteristics of cAMP signal transduction.

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Year:  1998        PMID： 9599411     DOI： 10.1006/scdb.1997.0221

Source DB:  PubMed          Journal:  Semin Cell Dev Biol        ISSN： 1084-9521            Impact factor:   7.727


  20 in total

1.  Understanding inositol pyrophosphate metabolism and function: kinetic characterization of the DIPPs.

Authors:  Rajagopal S Kilari; Jeremy D Weaver; Stephen B Shears; Stephen T Safrany
Journal:  FEBS Lett       Date:  2013-09-08       Impact factor: 4.124

2.  Channeling of cAMP in PDE-PKA Complexes Promotes Signal Adaptation.

Authors:  Nikhil Kumar Tulsian; Srinath Krishnamurthy; Ganesh Srinivasan Anand
Journal:  Biophys J       Date:  2017-06-20       Impact factor: 4.033

Review 3.  Cyclic nucleotide phosphodiesterases as targets for treatment of haematological malignancies.

Authors:  Adam Lerner; Paul M Epstein
Journal:  Biochem J       Date:  2006-01-01       Impact factor: 3.857

4.  Characterization of a catalytic ligand bridging metal ions in phosphodiesterases 4 and 5 by molecular dynamics simulations and hybrid quantum mechanical/molecular mechanical calculations.

Authors:  Ying Xiong; Hai-Ting Lu; Yongjian Li; Guang-Fu Yang; Chang-Guo Zhan
Journal:  Biophys J       Date:  2006-09-01       Impact factor: 4.033

5.  Ca2+/calcineurin-inhibited adenylyl cyclase, highly abundant in forebrain regions, is important for learning and memory.

Authors:  F A Antoni; M Palkovits; J Simpson; S M Smith; A L Leitch; R Rosie; G Fink; J M Paterson
Journal:  J Neurosci       Date:  1998-12-01       Impact factor: 6.167

6.  "Riddle Me This": Substrate Channeling Solves the Paradigms of cAMP-Dependent Activation of PKA.

Authors:  César A Ramírez-Sarmiento
Journal:  Biophys J       Date:  2017-06-20       Impact factor: 4.033

7.  Characterization of the structures of phosphodiesterase 10 binding with adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate by hybrid quantum mechanical/molecular mechanical calculations.

Authors:  Haiting Lu; Alan C Goren; Chang-Guo Zhan
Journal:  J Phys Chem B       Date:  2010-05-27       Impact factor: 2.991

Review 8.  EPAC proteins transduce diverse cellular actions of cAMP.

Authors:  Gillian Borland; Brian O Smith; Stephen J Yarwood
Journal:  Br J Pharmacol       Date:  2009-02-06       Impact factor: 8.739

9.  Exchange protein directly activated by cAMP (EPAC) interacts with the light chain (LC) 2 of MAP1A.

Authors:  Maria M Magiera; Mona Gupta; Catherine J Rundell; Nilima Satish; Isabelle Ernens; Stephen J Yarwood
Journal:  Biochem J       Date:  2004-09-15       Impact factor: 3.857

10.  Expression profiles of phosphodiesterase 4D splicing variants in osteoblastic cells.

Authors:  Chizumi Nomura-Furuwatari; Shigeyuki Wakitani; Yusuke Hashimoto; Yuuki Imai; Yoichi Ohta; Keisuke Nakagawa; Yoshihiro Nakao; Kazushi Takayama; Tomoya Manaka; Kunio Takaoka
Journal:  J Bone Miner Metab       Date:  2008-02-27       Impact factor: 2.626
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