| Literature DB >> 9599264 |
A C Alécio1, V da Silva Bolzani, M C Young, M J Kato, M Furlan.
Abstract
Bioactivity-guided fractionation of a CH2Cl2 extract from leaves of Piper hispidum (Piperaceae) yielded a new pyrrolidine amide, N-[7-(3',4'-methylenedioxyphenyl)-2(Z),4(Z)-heptadienoyl] pyrrolidine 1, in addition to two known amides N-[5-(3', 4'-methylenedioxyphenyl)-2(E)-pentadienoyl] pyrrolidine and N-[2-(3', 4'-methylenedioxy-6'-methoxyphenyl)-2(Z)-propenoyl]pyrrolidine. The structure of compound 1 was elucidated by interpretation of spectral data, including ES-MS. Compound 1 showed antifungal activity against Cladosporium sphaerospermum.Entities:
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Year: 1998 PMID: 9599264 DOI: 10.1021/np9703656
Source DB: PubMed Journal: J Nat Prod ISSN: 0163-3864 Impact factor: 4.050