| Literature DB >> 959827 |
E F Ellis, O Oelz, L J Roberts, N A Payne, B J Sweetman, A S Nies, J A Oates.
Abstract
When human platelets are aggregated by thrombin, material is released that rapidly contracts strips of spirally cut porcine coronary artery. Prevention of the contraction by indomethacin suggested mediation by a prostaglandin. The contraction produced by aggregating platelets was unlike those produced by prostaglandins E2, F2alpha, G2, or H2, but resembled that evoked by thromboxane A2, which is formed by platelets during aggregation.Entities:
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Year: 1976 PMID： 959827 DOI： 10.1126/science.959827
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728