Literature DB >> 9598119

Dihydroorotate dehydrogenase. Profile of a novel target for antiproliferative and immunosuppressive drugs.

M Löffler1, K Grein, W Knecht, A Klein, U Bergjohann.   

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Year:  1998        PMID: 9598119

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN: 0065-2598            Impact factor:   2.622


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  7 in total

1.  4SC-101, a novel small molecule dihydroorotate dehydrogenase inhibitor, suppresses systemic lupus erythematosus in MRL-(Fas)lpr mice.

Authors:  Onkar P Kulkarni; Sufyan G Sayyed; Claudia Kantner; Mi Ryu; Max Schnurr; Miklós Sárdy; Johann Leban; Ruediger Jankowsky; Aldo Ammendola; Robert Doblhofer; Hans-Joachim Anders
Journal:  Am J Pathol       Date:  2010-04-22       Impact factor: 4.307

2.  Defects in vesicle core induced by escherichia coli dihydroorotate dehydrogenase.

Authors:  Sheila G Couto; M Cristina Nonato; Antonio J Costa-Filho
Journal:  Biophys J       Date:  2007-11-09       Impact factor: 4.033

3.  Dihydro-orotate dehydrogenase is physically associated with the respiratory complex and its loss leads to mitochondrial dysfunction.

Authors:  JingXian Fang; Takeshi Uchiumi; Mikako Yagi; Shinya Matsumoto; Rie Amamoto; Shinya Takazaki; Haruyoshi Yamaza; Kazuaki Nonaka; Dongchon Kang
Journal:  Biosci Rep       Date:  2013-02-05       Impact factor: 3.840

4.  Protein instability and functional defects caused by mutations of dihydro-orotate dehydrogenase in Miller syndrome patients.

Authors:  JingXian Fang; Takeshi Uchiumi; Mikako Yagi; Shinya Matsumoto; Rie Amamoto; Toshiro Saito; Shinya Takazaki; Tomotake Kanki; Haruyoshi Yamaza; Kazuaki Nonaka; Dongchon Kang
Journal:  Biosci Rep       Date:  2012-12       Impact factor: 3.840

5.  Babesia bovis dihydroorotate dehydrogenase (BboDHODH) is a novel molecular target of drug for bovine babesiosis.

Authors:  Ketsarin Kamyingkird; Shinuo Cao; Tatsunori Masatani; Paul Franck Adjou Moumouni; Patrick Vudriko; Ahmed Abd El Moniem Mousa; Mohamad Alaa Terkawi; Yoshifumi Nishikawa; Ikuo Igarashi; Xuenan Xuan
Journal:  J Vet Med Sci       Date:  2013-11-01       Impact factor: 1.267

6.  Bombyx mori Dihydroorotate Dehydrogenase: Knockdown Inhibits Cell Growth and Proliferation via Inducing Cell Cycle Arrest.

Authors:  Erhu Zhao; Xiaolan Jiang; Hongjuan Cui
Journal:  Int J Mol Sci       Date:  2018-08-30       Impact factor: 5.923

7.  The Selective Oral Immunomodulator Vidofludimus in Patients with Active Rheumatoid Arthritis: Safety Results from the COMPONENT Study.

Authors:  Andreas Muehler; Hella Kohlhof; Manfred Groeppel; Daniel Vitt
Journal:  Drugs R D       Date:  2019-12
  7 in total

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