Literature DB >> 9596775

LcrG is required for efficient translocation of Yersinia Yop effector proteins into eukaryotic cells.

M R Sarker1, M P Sory, A P Boyd, M Iriarte, G R Cornelis.   

Abstract

Extracellular Yersinia disables the immune system of its host by injecting effector Yop proteins into host cells. We show that a Yersinia enterocolitica nonpolar lcrG mutant is severely impaired in the translocation of YopE, YopH, YopM, YpkA/YopO, and YopP into eukaryotic cells. LcrG is thus required for efficient internalization of all the known Yop effectors.

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Year:  1998        PMID： 9596775      PMCID： PMC108297          DOI： 10.1128/IAI.66.6.2976-2979.1998

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  36 in total

1.  The surface-located YopN protein is involved in calcium signal transduction in Yersinia pseudotuberculosis.

Authors:  A Forsberg; A M Viitanen; M Skurnik; H Wolf-Watz
Journal:  Mol Microbiol       Date:  1991-04       Impact factor: 3.501

2.  Analysis of virC, an operon involved in the secretion of Yop proteins by Yersinia enterocolitica.

Authors:  T Michiels; J C Vanooteghem; C Lambert de Rouvroit; B China; A Gustin; P Boudry; G R Cornelis
Journal:  J Bacteriol       Date:  1991-08       Impact factor: 3.490

3.  Intracellular targeting of the Yersinia YopE cytotoxin in mammalian cells induces actin microfilament disruption.

Authors:  R Rosqvist; A Forsberg; H Wolf-Watz
Journal:  Infect Immun       Date:  1991-12       Impact factor: 3.441

4.  Role of YopP in suppression of tumor necrosis factor alpha release by macrophages during Yersinia infection.

Authors:  A Boland; G R Cornelis
Journal:  Infect Immun       Date:  1998-05       Impact factor: 3.441

5.  Transcription of the yop regulon from Y. enterocolitica requires trans acting pYV and chromosomal genes.

Authors:  G Cornelis; J C Vanootegem; C Sluiters
Journal:  Microb Pathog       Date:  1987-05       Impact factor: 3.738

6.  Characterization of plasmids and plasmid-associated determinants of Yersinia enterocolitica pathogenesis.

Authors:  D A Portnoy; S L Moseley; S Falkow
Journal:  Infect Immun       Date:  1981-02       Impact factor: 3.441

7.  Molecular analysis of lcrGVH, the V antigen operon of Yersinia pestis.

Authors:  S B Price; K Y Leung; S S Barve; S C Straley
Journal:  J Bacteriol       Date:  1989-10       Impact factor: 3.490

8.  Analysis of the V antigen lcrGVH-yopBD operon of Yersinia pseudotuberculosis: evidence for a regulatory role of LcrH and LcrV.

Authors:  T Bergman; S Håkansson; A Forsberg; L Norlander; A Macellaro; A Bäckman; I Bölin; H Wolf-Watz
Journal:  J Bacteriol       Date:  1991-03       Impact factor: 3.490

9.  Identification of additional virulence determinants on the pYV plasmid of Yersinia enterocolitica W227.

Authors:  B Mulder; T Michiels; M Simonet; M P Sory; G Cornelis
Journal:  Infect Immun       Date:  1989-08       Impact factor: 3.441

10.  A wide-host-range suicide vector for improving reverse genetics in gram-negative bacteria: inactivation of the blaA gene of Yersinia enterocolitica.

Authors:  K Kaniga; I Delor; G R Cornelis
Journal:  Gene       Date:  1991-12-20       Impact factor: 3.688
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  16 in total

1.  LcrG-LcrV interaction is required for control of Yops secretion in Yersinia pestis.

Authors:  J S Matson; M L Nilles
Journal:  J Bacteriol       Date:  2001-09       Impact factor: 3.490

2.  Roles of LcrG and LcrV during type III targeting of effector Yops by Yersinia enterocolitica.

Authors:  K L DeBord; V T Lee; O Schneewind
Journal:  J Bacteriol       Date:  2001-08       Impact factor: 3.490

3.  Altered Ca(2+) regulation of Yop secretion in Yersinia enterocolitica after DNA adenine methyltransferase overproduction is mediated by Clp-dependent degradation of LcrG.

Authors:  Stefan Fälker; M Alexander Schmidt; Gerhard Heusipp
Journal:  J Bacteriol       Date:  2006-10       Impact factor: 3.490

Review 4.  The Yersinia deadly kiss.

Authors:  G R Cornelis
Journal:  J Bacteriol       Date:  1998-11       Impact factor: 3.490

5.  Identification of SycN, YscX, and YscY, three new elements of the Yersinia yop virulon.

Authors:  M Iriarte; G R Cornelis
Journal:  J Bacteriol       Date:  1999-01       Impact factor: 3.490

6.  YopJ of Yersinia spp. is sufficient to cause downregulation of multiple mitogen-activated protein kinases in eukaryotic cells.

Authors:  L E Palmer; A R Pancetti; S Greenberg; J B Bliska
Journal:  Infect Immun       Date:  1999-02       Impact factor: 3.441

7.  The gene coding for the Hrp pilus structural protein is required for type III secretion of Hrp and Avr proteins in Pseudomonas syringae pv. tomato.

Authors:  W Wei; A Plovanich-Jones; W L Deng; Q L Jin; A Collmer; H C Huang; S Y He
Journal:  Proc Natl Acad Sci U S A       Date:  2000-02-29       Impact factor: 11.205

8.  Role of YopP in suppression of tumor necrosis factor alpha release by macrophages during Yersinia infection.

Authors:  A Boland; G R Cornelis
Journal:  Infect Immun       Date:  1998-05       Impact factor: 3.441

9.  The LcrG Tip Chaperone Protein of the Yersinia pestis Type III Secretion System Is Partially Folded.

Authors:  Sukanya Chaudhury; Clarice de Azevedo Souza; Gregory V Plano; Roberto N De Guzman
Journal:  J Mol Biol       Date:  2015-08-07       Impact factor: 5.469

Review 10.  The virulence plasmid of Yersinia, an antihost genome.

Authors:  G R Cornelis; A Boland; A P Boyd; C Geuijen; M Iriarte; C Neyt; M P Sory; I Stainier
Journal:  Microbiol Mol Biol Rev       Date:  1998-12       Impact factor: 11.056
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