Literature DB >> 9592769

Epitope mapping by surface plasmon resonance in the BIAcore.

B Johne1.   

Abstract

An epitope may be defined as a specific site on an antigen module characterized by the binding of one monoclonal antibody (MAb). Epitope mapping by surface plasmon resonance in the BIAcore biosensor may be performed to characterize an antigen or a group of specific MAbs or both. This article describes the BIAcore instrument and methods for such mapping. Examples include molecular interaction studies with simple and complex proteins, such as myoglobin and calprotectin, respectively.

Mesh:

Year:  1998        PMID: 9592769     DOI: 10.1007/BF02752698

Source DB:  PubMed          Journal:  Mol Biotechnol        ISSN: 1073-6085            Impact factor:   2.695


  6 in total

1.  Biospecific interaction analysis using surface plasmon resonance detection applied to kinetic, binding site and concentration analysis.

Authors:  L G Fägerstam; A Frostell-Karlsson; R Karlsson; B Persson; I Rönnberg
Journal:  J Chromatogr       Date:  1992-04-24

2.  Detection of antigen-antibody interactions by surface plasmon resonance. Application to epitope mapping.

Authors:  L G Fägerstam; A Frostell; R Karlsson; M Kullman; A Larsson; M Malmqvist; H Butt
Journal:  J Mol Recognit       Date:  1990 Oct-Dec       Impact factor: 2.137

3.  Kinetic analysis of monoclonal antibody-antigen interactions with a new biosensor based analytical system.

Authors:  R Karlsson; A Michaelsson; L Mattsson
Journal:  J Immunol Methods       Date:  1991-12-15       Impact factor: 2.303

4.  Epitope mapping and binding kinetics of monoclonal antibodies studied by real time biospecific interaction analysis using surface plasmon resonance.

Authors:  B Johne; M Gadnell; K Hansen
Journal:  J Immunol Methods       Date:  1993-04-02       Impact factor: 2.303

Review 5.  Structural and functional approaches to the study of protein antigenicity.

Authors:  M H Van Regenmortel
Journal:  Immunol Today       Date:  1989-08

6.  Colloidal gold conjugated monoclonal antibodies, studied in the BIAcore biosensor and in the Nycocard immunoassay format.

Authors:  B Johne; K Hansen; E Mørk; J Holtlund
Journal:  J Immunol Methods       Date:  1995-06-14       Impact factor: 2.303

  6 in total
  3 in total

1.  Epitope-specific immune recognition of the nontypeable Haemophilus influenzae outer membrane protein 26.

Authors:  Duangkamol Kunthalert; Laura A Novotny; Helen M Massa; Glen C Ulett; Lauren O Bakaletz; Jennelle M Kyd; Allan W Cripps
Journal:  Hum Vaccin Immunother       Date:  2013-01-04       Impact factor: 3.452

2.  Diversity of PR3-ANCA epitope specificity in Wegener's granulomatosis. Analysis using the biosensor technology.

Authors:  Agnieszka A Rarok; Ymke M van der Geld; Coen A Stegeman; Pieter C Limburg; Cees G M Kallenberg
Journal:  J Clin Immunol       Date:  2003-11       Impact factor: 8.317

3.  Staphylococcus aureus manganese transport protein C is a highly conserved cell surface protein that elicits protective immunity against S. aureus and Staphylococcus epidermidis.

Authors:  Annaliesa S Anderson; Ingrid L Scully; Yekaterina Timofeyeva; Ellen Murphy; Lisa K McNeil; Terri Mininni; Lorna Nuñez; Marjolaine Carriere; Christine Singer; Deborah A Dilts; Kathrin U Jansen
Journal:  J Infect Dis       Date:  2012-04-02       Impact factor: 5.226

  3 in total

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