Literature DB >> 9592560

Epoxyquinomicins A, B, C and D, new antibiotics from Amycolatopsis. I. Taxonomy, fermentation, isolation and antimicrobial activities.

N Matsumoto1, T Tsuchida, M Umekita, N Kinoshita, H Iinuma, T Sawa, M Hamada, T Takeuchi.   

Abstract

A new structural class of the antibiotic, epoxyquinomicins A, B, C and D were isolated from the culture broth of the strain MK299-95F4, which was related to Amycolatopsis sulphurea. Antimicrobial activity of epoxyquinomicins A and B were weak against Gram-positive bacteria, and epoxyquinomicins C and D showed almost no antimicrobial activity and no cytotoxicity. All these antibiotics showed improvement of collagen induced arthritis in vivo.

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Year:  1997        PMID： 9592560     DOI： 10.7164/antibiotics.50.900

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  5 in total

1.  Identification of a novel mannose-capped lipoarabinomannan from Amycolatopsis sulphurea.

Authors:  Kevin J C Gibson; Martine Gilleron; Patricia Constant; Germain Puzo; Jérôme Nigou; Gurdyal S Besra
Journal:  Biochem J       Date:  2003-06-15       Impact factor: 3.857

2.  A comparative analysis of the sugar phosphate cyclase superfamily involved in primary and secondary metabolism.

Authors:  Xiumei Wu; Patricia M Flatt; Oliver Schlörke; Axel Zeeck; Tohru Dairi; Taifo Mahmud
Journal:  Chembiochem       Date:  2007-01-22       Impact factor: 3.164

3.  Diversity of antibiotic-active bacteria associated with the brown alga Laminaria saccharina from the Baltic Sea.

Authors:  Jutta Wiese; Vera Thiel; Kerstin Nagel; Tim Staufenberger; Johannes F Imhoff
Journal:  Mar Biotechnol (NY)       Date:  2008-10-15       Impact factor: 3.619

Review 4.  Anticancer Activity of Novel NF-kappa B Inhibitor DHMEQ by Intraperitoneal Administration.

Authors:  Kazuo Umezawa; Andrzej Breborowicz; Shamil Gantsev
Journal:  Oncol Res       Date:  2020-06-23       Impact factor: 5.574

Review 5.  Secondary Metabolites of the Genus Amycolatopsis: Structures, Bioactivities and Biosynthesis.

Authors:  Zhiqiang Song; Tangchang Xu; Junfei Wang; Yage Hou; Chuansheng Liu; Sisi Liu; Shaohua Wu
Journal:  Molecules       Date:  2021-03-26       Impact factor: 4.411
  5 in total

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