Literature DB >> 9591955

Preoperative features of patients with exfoliation glaucoma and primary open-angle glaucoma. The AHEPA study.

A G Konstas1, I Tsatsos, A Kardasopoulos, T Bufidis, G Maskaleris.   

Abstract

PURPOSE: To describe and compare the preoperative characteristics of Greek patients with exfoliation glaucoma (EXG) and primary open-angle glaucoma (POAG).
METHODS: We prospectively investigated the preoperative features of 100 consecutive patients undergoing filtration surgery for either EXG, or POAG. We compared 74 patients with EXG and 26 with POAG.
RESULTS: EXG patients were older (68.2 vs 62.4 years; p<0.05) and more often from the countryside (73%). Both glaucomas showed a preponderance for males, similar frequencies of positive family history and systemic disorders, with the exception of diabetes which was more common in POAG (19.2% vs 5.4%). The first IOP measurement, before treatment, was significantly higher in EXG (40.4 mm Hg) compared with POAG (33.9 mm Hg). Despite a shorter duration of medical therapy (25 vs 65 months) and more topical drugs EXG patients exhibited higher mean preoperative IOP (36 vs 27.8 mm Hg for POAG; p<0.05). EXG patients had significantly worse visual acuity than POAG (0.4 vs 0.6; p<0.05) and worse compliance to medical therapy (48%) compared to POAG (33%).
CONCLUSION: Significant differences in preoperative features distinguish EXG from POAG.

Entities:  

Mesh:

Year:  1998        PMID: 9591955     DOI: 10.1034/j.1600-0420.1998.760217.x

Source DB:  PubMed          Journal:  Acta Ophthalmol Scand        ISSN: 1395-3907


  12 in total

1.  Pseudoexfoliation syndrome: analysis of systemic comorbidities of 325 PEX-positive patients compared with 911 PEX-negative patients.

Authors:  Elizabeth Scharfenberg; Franziska G Rauscher; Petra Meier; Dirk Hasenclever
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2019-08-16       Impact factor: 3.117

Review 2.  [PEX syndrome. Clinical diagnosis and systemic manifestations].

Authors:  E Scharfenberg; U Schlötzer-Schrehardt
Journal:  Ophthalmologe       Date:  2012-10       Impact factor: 1.059

Review 3.  Exfoliation syndrome in sub-Saharan Africa.

Authors:  Olusola O Olawoye; Louis R Pasquale; Robert Ritch
Journal:  Int Ophthalmol       Date:  2014-05-21       Impact factor: 2.031

Review 4.  [Diagnosis and therapy of pseudoexfoliation glaucoma].

Authors:  A G M Jünemann
Journal:  Ophthalmologe       Date:  2012-10       Impact factor: 1.059

5.  Association of ocular pseudoexfoliation syndrome with ischaemic heart disease, arterial hypertension and diabetes mellitus.

Authors:  Martynas Spečkauskas; Abdonas Tamošiūnas; Vytautas Jašinskas
Journal:  Acta Ophthalmol       Date:  2012-05-02       Impact factor: 3.761

6.  Intraocular pressure following phacoemulsification in patients with and without exfoliation syndrome: a 2 year prospective study.

Authors:  K F Damji; A G P Konstas; J M Liebmann; W G Hodge; N G Ziakas; S Giannikakis; G Mintsioulis; A Merkur; Y Pan; R Ritch
Journal:  Br J Ophthalmol       Date:  2006-05-03       Impact factor: 4.638

7.  Increase of carotid artery stiffness and decrease of baroreflex sensitivity in exfoliation syndrome and glaucoma.

Authors:  Z Visontai; B Merisch; M Kollai; G Holló
Journal:  Br J Ophthalmol       Date:  2006-02-17       Impact factor: 4.638

8.  Short-term fluctuation of intraocular pressure is higher in patients with pseudoexfoliation syndrome despite similar mean intraocular pressure: a retrospective case-control study.

Authors:  Cord Huchzermeyer; Folkert Horn; Robert Lämmer; Christian Y Mardin; Anselm G M Jünemann
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2014-10-14       Impact factor: 3.117

9.  Serum heparan sulfate and chondroitin sulfate concentrations in patients with newly diagnosed exfoliative glaucoma.

Authors:  Vesna D Maric; Marija M Bozic; Andja M Cirkovic; Sanja Dj Stankovic; Ivan S Marjanovic; Anita D Grgurevic
Journal:  PeerJ       Date:  2019-05-23       Impact factor: 2.984

Review 10.  Ocular pseudoexfoliation syndrome and vascular disease: a systematic review and meta-analysis.

Authors:  Wei Wang; Miao He; Minwen Zhou; Xiulan Zhang
Journal:  PLoS One       Date:  2014-03-25       Impact factor: 3.240

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