Literature DB >> 9589308

The clinical utility of randomized controlled trials.

G T Wilson1.   

Abstract

OBJECTIVE: Efficacy studies using randomized controlled trials (RCTs), on which empirically supported treatments are based, are often rejected as having little if any relevance to clinical practice. RCTs are faulted for allegedly excluding poor prognosis patients and therapists and treatments that are unrepresentative of clinical practice.
METHODS: Evidence on the generalizability of findings from RCTs to diverse patient populations, different therapists, and varied clinical settings is critically evaluated.
RESULTS: Existing research indicates that RCTs commonly include patients with multiple problems and levels of disturbance as severe as patients in clinical settings. DISCUSSION: The applicability of the findings of RCTs to clinical practice will be a changing function of the nature of the particular study and clinical setting to which the results are to be generalized. Future research should address the clinical utility of the findings of efficacy studies across different patient populations, therapists, and treatment methods.

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Year:  1998        PMID: 9589308     DOI: 10.1002/(sici)1098-108x(199807)24:1<13::aid-eat2>3.0.co;2-3

Source DB:  PubMed          Journal:  Int J Eat Disord        ISSN: 0276-3478            Impact factor:   4.861


  2 in total

1.  Subtyping women with bulimia nervosa along dietary and negative affect dimensions: a replication in a treatment-seeking sample.

Authors:  C M Grilo; R M Masheb; R M Berman
Journal:  Eat Weight Disord       Date:  2001-03       Impact factor: 3.008

2.  Can treatment trial samples be representative?

Authors:  Jackie A Wales; Robert L Palmer; Christopher G Fairburn
Journal:  Behav Res Ther       Date:  2009-07-10
  2 in total

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