Literature DB >> 9589255

Validation of a diabetic wound classification system. The contribution of depth, infection, and ischemia to risk of amputation.

D G Armstrong1, L A Lavery, L B Harkless.   

Abstract

OBJECTIVE: To validate a wound classification instrument that includes assessment of depth, infection, and ischemia based on the eventual outcome of the wound. RESEARCH DESIGN AND METHODS: We evaluated the medical records of 360 diabetic patients presenting for care of foot wounds at a multidisciplinary tertiary care foot clinic. As per protocol, all patients had a standardized evaluation to assess wound depth, sensory neuropathy, vascular insufficiency, and infection. Patients were assessed at 6 months after their initial evaluation to see whether an amputation had been performed.
RESULTS: There was a significant overall trend toward increased prevalence of amputations as wounds increased in both depth (chi 2trend = 143.1, P < 0.001) and stage (chi 2trend = 91.0, P < 0.001). This was true for every subcategory as well with the exception of noninfected, nonischemic ulcers. There were no amputations performed within this stage during the follow-up period. Patients were more than 11 times more likely to receive a midfoot or higher level amputation if their wound probed to bone (18.3 vs. 2.0%, P < 0.001, chi 2 = 31.5, odds ratio (OR) = 11.1, CI = 4.0-30.3). Patients with infection and ischemia were nearly 90 times more likely to receive a midfoot or higher amputation compared with patients in less advanced wound stages (76.5 vs. 3.5%, P < 0.001, chi 2 = 133.5, OR = 89.6, CI = 25-316).
CONCLUSIONS: Outcomes deteriorated with increasing grade and stage of wounds when measured using the University of Texas Wound Classification System.

Entities:  

Mesh:

Year:  1998        PMID: 9589255     DOI: 10.2337/diacare.21.5.855

Source DB:  PubMed          Journal:  Diabetes Care        ISSN: 0149-5992            Impact factor:   19.112


  157 in total

Review 1.  Healing the diabetic wound and keeping it healed: modalities for the early 21st century.

Authors:  Matthew J Claxton; David G Armstrong; Andrew J M Boulton
Journal:  Curr Diab Rep       Date:  2002-12       Impact factor: 4.810

2.  CO2 laser for the treatment of diabetic foot ulcers with exposed bone. A consecutive series of type 2 diabetic patients.

Authors:  M Monami; C Mirabella; A Scatena; B Nreu; S Zannoni; S Aleffi; L Giannoni; E Mannucci
Journal:  J Endocrinol Invest       Date:  2017-03-04       Impact factor: 4.256

3.  [Peripheral artery disease and disorders of microcirculation in patients with diabetes mellitus].

Authors:  M Dreyer
Journal:  Internist (Berl)       Date:  2011-05       Impact factor: 0.743

Review 4.  Risk assessment of the diabetic foot and wound.

Authors:  Stephanie Wu; David G Armstrong
Journal:  Int Wound J       Date:  2005-03       Impact factor: 3.315

Review 5.  Diabetic foot infections: stepwise medical and surgical management.

Authors:  David G Armstrong; Benjamin A Lipsky
Journal:  Int Wound J       Date:  2004-06       Impact factor: 3.315

Review 6.  Classification of wounds of the diabetic foot.

Authors:  D G Armstrong; E J Peters
Journal:  Curr Diab Rep       Date:  2001-12       Impact factor: 4.810

Review 7.  Diabetic neuropathy: clinical features, etiology, and therapy.

Authors:  David Podwall; Clifton Gooch
Journal:  Curr Neurol Neurosci Rep       Date:  2004-01       Impact factor: 5.081

8.  Impaired lower extremity wound healing secondary to sirolimus after kidney transplantation.

Authors:  J George Devries; Rachel C Collier; Jeffrey A Niezgoda; Shawn Sanicola; John P Simanonok
Journal:  J Am Col Certif Wound Spec       Date:  2009-06-23

9.  Maggot debridement therapy with Lucilia cuprina: a comparison with conventional debridement in diabetic foot ulcers.

Authors:  Aaron G Paul; Nazni W Ahmad; H L Lee; Ashraff M Ariff; Masri Saranum; Amara S Naicker; Zulkiflee Osman
Journal:  Int Wound J       Date:  2009-02       Impact factor: 3.315

10.  From ulcer to infection: an update on clinical practice and adjunctive treatments of diabetic foot ulcers.

Authors:  C Abad; N Safdar
Journal:  Curr Infect Dis Rep       Date:  2012-10       Impact factor: 3.725

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