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Literature DB >> 958504

The molecular weights of plasma and intestinal kallikreins in rats.

I J Zeitlin, Y N Singh, F Lembeck, M Theiler.

Abstract

1. The molecular weights of kallikreins of rat intestine and rat plasma have been estimated using gel filtration. 2. Extracts of pooled tissue from rat jejunum, ileum, caecum and colon activated by autolytic processes gave a single peak of kallikrein activity with a molecular weights of 33000. 3. Acid-activated rat plasma gave two peaks of kallikrein activity with molecular weight of 125000 and 61500. 4. Rat intestinal tissue contains a kinin forming enzyme having a molecular weight similar to those of glandular kallikreins and different from those of the rat plasma kallikreins.

Entities: Disease Species

Mesh：

Substances：
Kallikreins

Year: 1976 PMID： 958504 DOI： 10.1007/BF00499221

Source DB: PubMed Journal: Naunyn Schmiedebergs Arch Pharmacol ISSN： 0028-1298 Impact factor: 3.000

11 in total

1. A STABLE SUBSTRATE FOR THE ASSAY OF PLASMA KININ-FORMING ENZYMES.

Authors: E AMUNDSEN; K NUSTAD; B WAALER
Journal: Br J Pharmacol Chemother Date: 1963-12

2. The fibrin plate method for estimating fibrinolytic activity.

Authors: T ASTRUP; S MULLERTZ
Journal: Arch Biochem Biophys Date: 1952-10 Impact factor: 4.013

3. Observations on intrinsic kinin-forming factors in human plasma: the effect of acid, acetone, chloroform, heat and euglobulin separation on kinin formation.

Authors: V Eisen
Journal: J Physiol Date: 1963-05 Impact factor: 5.182

The molecular weights of plasma and intestinal kallikreins in rats.

1. A STABLE SUBSTRATE FOR THE ASSAY OF PLASMA KININ-FORMING ENZYMES.

2. The fibrin plate method for estimating fibrinolytic activity.

3. Observations on intrinsic kinin-forming factors in human plasma: the effect of acid, acetone, chloroform, heat and euglobulin separation on kinin formation.

4. Colon kallikrein, its relation to the plasma enzyme.

5. Pharmacological characterization of kinin-forming activity in rat intestinal tissue.

6. Kinin-forming and destroying activities of cell homogenates.

7. The gel-filtration behaviour of proteins related to their molecular weights over a wide range.

8. Determination of plasmakinin & kininogen levels in man.

9. Mobilization of tissue kallikrein in inflammatory disease of the colon.

10. Estimation of the molecular weights of proteins by Sephadex gel-filtration.

1. An unpublished work of Stephen Hales (1677-1761) [proceedings].

2. The assay of tissue kallikrein in rat intestine [proceedings].

3. Kinins stimulate net chloride secretion by the rat colon.

4. Changes in colonic tissue levels of inflammatory mediators in a guinea-pig model of immune colitis.

5. Mobilization of colonic kallikrein following pelvic nerve stimulation in the atropinized cat.

6. The effect of diet on tissue levels of kinin-forming enzyme in blood-free rat gastro-intestinal tract.