Literature DB >> 9584933

Metabolic changes in the brain during transient ischemia measured with microdialysis.

C S Robertson1, S P Gopinath, M Uzura, A B Valadka, J C Goodman.   

Abstract

Forty-four patients with severe head injury were monitored for episodes of cerebral ischemia using jugular venous oxygen saturation (sjvO2), brain tissue pO2 (ti-pO2), and a microdialysis probe. The concentration of lactate and glucose were measured in the microdialysate. A total of 10 episodes of global ischemia were observed. The characteristic pattern of a simultaneous decrease in sjvO2 and brain ti-pO2 with an increase in the concentration of lactate occurred in all 10 patients. In addition, 3 episodes of regional ischemia were observed. Although brain ti-pO2 decreased to very low values and the concentration of lactate increased in the microdialysate, sjvO2 remained unchanged. Brain ti-pO2 adds another dimension to our cerebral monitoring by allowing the detection of regional cerebral ischemia.

Entities:  

Mesh：

Substances：

Year:  1998        PMID： 9584933     DOI： 10.1080/01616412.1998.11740618

Source DB:  PubMed          Journal:  Neurol Res        ISSN： 0161-6412            Impact factor:   2.448


  11 in total

Review 1.  Lung microdialysis--a powerful tool for the determination of exogenous and endogenous compounds in the lower respiratory tract (mini-review).

Authors:  Markus Zeitlinger; Markus Müller; Christian Joukhadar
Journal:  AAPS J       Date:  2005-10-22       Impact factor: 4.009

Review 2.  Regional brain monitoring in the neurocritical care unit.

Authors:  Jennifer Frontera; Wendy Ziai; Kristine O'Phelan; Peter D Leroux; Peter J Kirkpatrick; Michael N Diringer; Jose I Suarez
Journal:  Neurocrit Care       Date:  2015-06       Impact factor: 3.210

3.  Interaction between brain chemistry and physiology after traumatic brain injury: impact of autoregulation and microdialysis catheter location.

Authors:  Ivan Timofeev; Marek Czosnyka; Keri L H Carpenter; Jurgens Nortje; Peter J Kirkpatrick; Pippa G Al-Rawi; David K Menon; John D Pickard; Arun K Gupta; Peter J Hutchinson
Journal:  J Neurotrauma       Date:  2011-06       Impact factor: 5.269

4.  Intracerebral monitoring of silent infarcts after subarachnoid hemorrhage.

Authors:  Raimund Helbok; Ravi Chandra Madineni; Michael J Schmidt; Pedro Kurtz; Luis Fernandez; Sang-Bae Ko; Alex Choi; Morgan R Stuart; E Sander Connolly; Kiwon Lee; Neeraj Badjatia; Stephan A Mayer; Alexander G Khandji; Jan Claassen
Journal:  Neurocrit Care       Date:  2011-04       Impact factor: 3.210

5.  Multimodal neuromonitoring in a patient with aneurysmal subarachnoid hemorrhage associated with aortic coarctation.

Authors:  Raimund Helbok; Ronny Beer; Andreas Chemelli; Florian Sohm; Gregor Broessner; Peter Lackner; Martin Sojer; Bettina Pfausler; Claudius Thomé; Erich Schmutzhard
Journal:  Neurocrit Care       Date:  2011-06       Impact factor: 3.210

6.  My paper 20 years later: cerebral venous oxygen saturation studied with bilateral samples in the internal jugular veins.

Authors:  N Stocchetti; S Magnoni; E R Zanier
Journal:  Intensive Care Med       Date:  2015-01-23       Impact factor: 17.440

7.  Increases in GABA concentrations during cerebral ischaemia: a microdialysis study of extracellular amino acids.

Authors:  P J Hutchinson; M T O'Connell; P G Al-Rawi; C R Kett-White; A K Gupta; L B Maskell; J D Pickard; P J Kirkpatrick
Journal:  J Neurol Neurosurg Psychiatry       Date:  2002-01       Impact factor: 10.154

8.  Investigation of the effect of chlormethiazole on cerebral chemistry in neurosurgical patients: a combined study of microdialysis and a neuroprotective agent.

Authors:  P J Hutchinson; M T O'Connell; J P Coles; D A Chatfield; M R Coleman; P G Al-Rawi; C R Kett-White; A K Gupta; D K Menon; S J Boniface; M Heazell; P J Kirkpatrick; J D Pickard
Journal:  Br J Clin Pharmacol       Date:  2002-03       Impact factor: 4.335

Review 9.  Monitoring of brain and systemic oxygenation in neurocritical care patients.

Authors:  Mauro Oddo; Julian Bösel
Journal:  Neurocrit Care       Date:  2014-12       Impact factor: 3.210

10.  A review of the current treatment methods for posthaemorrhagic hydrocephalus of infants.

Authors:  David Shooman; Howard Portess; Owen Sparrow
Journal:  Cerebrospinal Fluid Res       Date:  2009-01-30
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.