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Literature DB >> 9584616

Iron and copper transport in yeast and its relevance to human disease.

Abstract

Recent progress in the field of copper and iron metabolism has resulted from a convergence of human and yeast genetics. The mechanisms of iron and copper transport are remarkably conserved between yeast and humans. Studies of the yeast homologs of human disease genes involved in metal homeostasis have shed light on the pathophysiology of these disorders.

Entities: Chemical Species

Mesh：

Substances：
Copper
Iron

Year: 1998 PMID： 9584616 DOI： 10.1016/s0968-0004(98)01192-x

Source DB: PubMed Journal: Trends Biochem Sci ISSN： 0968-0004 Impact factor: 13.807

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Cited

45 in total

1. High-level mitochondriology at high altitude. Workshop on mitochondrial (dys-)function.

Authors: R N Lightowlers; R Lill
Journal: EMBO Rep Date: 2001-12 Impact factor: 8.807

2. Selective determination of mitochondrial chelatable iron in viable cells with a new fluorescent sensor.

Authors: Frank Petrat; Daniela Weisheit; Martina Lensen; Herbert de Groot; Reiner Sustmann; Ursula Rauen
Journal: Biochem J Date: 2002-02-15 Impact factor: 3.857

3. Subcellular distribution of chelatable iron: a laser scanning microscopic study in isolated hepatocytes and liver endothelial cells.

Authors: F Petrat; H de Groot; U Rauen
Journal: Biochem J Date: 2001-05-15 Impact factor: 3.857

Review 4. Oxidative stress in microorganisms--I. Microbial vs. higher cells--damage and defenses in relation to cell aging and death.

Authors: K Sigler; J Chaloupka; J Brozmanová; N Stadler; M Höfer
Journal: Folia Microbiol (Praha) Date: 1999 Impact factor: 2.099

Review 5. Friedreich ataxia: an overview.

Authors: M B Delatycki; R Williamson; S M Forrest
Journal: J Med Genet Date: 2000-01 Impact factor: 6.318

6. A family knockout of all four Drosophila metallothioneins reveals a central role in copper homeostasis and detoxification.

Authors: Dieter Egli; Hasmik Yepiskoposyan; Anand Selvaraj; Kuppusamy Balamurugan; Rama Rajaram; Andreas Simons; Gerd Multhaup; Simone Mettler; Alla Vardanyan; Oleg Georgiev; Walter Schaffner
Journal: Mol Cell Biol Date: 2006-03 Impact factor: 4.272

Iron and copper transport in yeast and its relevance to human disease.

1. High-level mitochondriology at high altitude. Workshop on mitochondrial (dys-)function.

2. Selective determination of mitochondrial chelatable iron in viable cells with a new fluorescent sensor.

3. Subcellular distribution of chelatable iron: a laser scanning microscopic study in isolated hepatocytes and liver endothelial cells.

Review 4. Oxidative stress in microorganisms--I. Microbial vs. higher cells--damage and defenses in relation to cell aging and death.

Review 5. Friedreich ataxia: an overview.

6. A family knockout of all four Drosophila metallothioneins reveals a central role in copper homeostasis and detoxification.

Review 7. Siderophore-based iron acquisition and pathogen control.

Review 8. The yeast connection to Friedreich ataxia.

9. Identification of the molecular mechanisms underlying the cytotoxic action of a potent platinum metallointercalator.

10. FRD3, a member of the multidrug and toxin efflux family, controls iron deficiency responses in Arabidopsis.