Literature DB >> 9584492

[A case of mild-type myotonic dystrophy with dementia and severe arteriosclerosis obliterans].

M Horiki1, A Morishima, H Yamagata, H Rakugi, H Ikegami, T Miki, T Ogihara.   

Abstract

A 70-year-old man, with mild-type myotonic dystrophy (MyD) diagnosed by molecular genetic analysis when he was 68 years old, complained of worsening intermittent claudication during the past 2 years. Doppler examination revealed severe stenosis and obstruction in his leg arteries, which we diagnosed as arteriosclerosis obliterans (ASO). We then found him to be suffering from dementia, which was confirmed by dementia scale tests (Mini Mental State, 20/30; Hasegawas' Dementia Scale-Revision, 15/30). Even in mild-type MyD, as MyD is one of the progeria syndromes, the abnormal genes of MyD may accelerate the aging processes.

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Year:  1998        PMID: 9584492     DOI: 10.3143/geriatrics.35.136

Source DB:  PubMed          Journal:  Nihon Ronen Igakkai Zasshi        ISSN: 0300-9173


  1 in total

1.  CADASIL-like leukodystrophy and symptomatic cerebral infarction in myotonic dystrophy type 1.

Authors:  Bin Liu; Chun-Lin Yang; Xiao-Li Li; Min Zhang; Yan-Bin Li; Rui-Sheng Duan
Journal:  CNS Neurosci Ther       Date:  2022-07-03       Impact factor: 7.035

  1 in total

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