| Literature DB >> 9584492 |
M Horiki1, A Morishima, H Yamagata, H Rakugi, H Ikegami, T Miki, T Ogihara.
Abstract
A 70-year-old man, with mild-type myotonic dystrophy (MyD) diagnosed by molecular genetic analysis when he was 68 years old, complained of worsening intermittent claudication during the past 2 years. Doppler examination revealed severe stenosis and obstruction in his leg arteries, which we diagnosed as arteriosclerosis obliterans (ASO). We then found him to be suffering from dementia, which was confirmed by dementia scale tests (Mini Mental State, 20/30; Hasegawas' Dementia Scale-Revision, 15/30). Even in mild-type MyD, as MyD is one of the progeria syndromes, the abnormal genes of MyD may accelerate the aging processes.Entities:
Mesh:
Year: 1998 PMID: 9584492 DOI: 10.3143/geriatrics.35.136
Source DB: PubMed Journal: Nihon Ronen Igakkai Zasshi ISSN: 0300-9173