Literature DB >> 9584406

Cochinolide, a new gamma-alkylidene bicyclic butenolide with antiviral activity, and its beta-glucopyranoside from Homalium cochinchinensis.

T Ishikawa1, K Nishigaya, H Uchikoshi, I S Cheng.   

Abstract

A new gamma-alkylidene bicyclic butenolide designated as cochinolide (1) and its beta-glucopyranoside (3) were isolated from the root bark of Homalium cochinchinensis (Flacoutiaceae). Their structures, except absolute stereochemistries, were determined by spectroscopic means. Cochinolide (1) showed moderate antiviral activities against HSV-1 and -2.

Entities:  

Mesh：

Substances：

Year:  1998        PMID： 9584406     DOI： 10.1021/np970341z

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  4 in total

1.  7,9-Diaryl-1,6,8-trioxaspiro[4.5]dec-3-en-2-ones: readily accessible and highly potent anticancer compounds.

Authors:  Michael P D'Erasmo; William B Smith; Alberto Munoz; Poornima Mohandas; Andrew S Au; Jason J Marineau; Luis E N Quadri; James E Bradner; Ryan P Murelli
Journal:  Bioorg Med Chem Lett       Date:  2014-06-12       Impact factor: 2.823

2.  Spermidine alkaloid and glycosidic constituents of Vietnamese Homalium cochinchinensis.

Authors:  Ermias Mekuria Addo; Yulin Ren; Gerardo D Anaya-Eugenio; Tran Ngoc Ninh; Harinantenaina L Rakotondraibe; Esperanza J Carcache de Blanco; Djaja D Soejarto; A Douglas Kinghorn
Journal:  Phytochem Lett       Date:  2021-04-15       Impact factor: 1.873

Review 3.  Emerging paradigms of viral diseases and paramount role of natural resources as antiviral agents.

Authors:  R Sagaya Jansi; Ameer Khusro; Paul Agastian; Ahmed Alfarhan; Naif Abdullah Al-Dhabi; Mariadhas Valan Arasu; Rajakrishnan Rajagopal; Damia Barcelo; Amal Al-Tamimi
Journal:  Sci Total Environ       Date:  2020-11-07       Impact factor: 7.963

4.  (4R,6S)-2-Dihydromenisdaurilide is a Butenolide that Efficiently Inhibits Hepatitis C Virus Entry.

Authors:  Chueh-Yao Chung; Ching-Hsuan Liu; Guey-Horng Wang; Alagie Jassey; Chia-Lin Li; Lei Chen; Ming-Hong Yen; Chun-Ching Lin; Liang-Tzung Lin
Journal:  Sci Rep       Date:  2016-07-18       Impact factor: 4.379
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.