| Literature DB >> 9584401 |
N Tsuchiya1, A Sato, T Hata, N Sato, K Sasagawa, T Kobayashi.
Abstract
Novel scalarane sesterterpenes (1-4) were isolated from a sponge, Hyrtios erecta (order Dictyoceratida). They were characterized by means of spectral analyses, X-ray crystallography, and chemical reactions. Compound 1 showed potent in vitro and in vivo antitumor activities. In addition, the structure-activity relationship was also discussed using computer-assisted structure matching of 1 and aragusterols.Entities:
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Year: 1998 PMID： 9584401 DOI： 10.1021/np970462z
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050