| Literature DB >> 9583163 |
Abstract
Daily bilateral microinjections of 15 or 45 mcg of amphetamine into the globus pallidus of rats within three weeks inhibited the realization of conditioned avoidance in a shuttle-box. The dose of 15 mcg was most effective. There were no changes in locomotor activity. In contrast to the results obtained earlier in the experiments with similar neostriatal microinjections, no stimulatory dopaminergic effects (stereotyped behavior) were observed. The differences are discussed in the roles of the pallidal and neostriatal dopaminergic systems in regulation of behavior.Entities:
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Year: 1998 PMID: 9583163
Source DB: PubMed Journal: Zh Vyssh Nerv Deiat Im I P Pavlova ISSN: 0044-4677 Impact factor: 0.437