Literature DB >> 9582938

Emerging targets for the development of novel antifungal therapeutics.

A H Groll1, A J De Lucca, T J Walsh.   

Abstract

Invasive mycoses have become important causes of morbidity and mortality in immunocompromised patients. New approaches for antifungal therapy are required to meet the challenges imposed by these life-threatening infections. Such approaches are being developed through identification of novel biochemical and molecular targets of pathogenic fungi.

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Year:  1998        PMID： 9582938     DOI： 10.1016/s0966-842x(97)01206-7

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN： 0966-842X            Impact factor:   17.079


  15 in total

Review 1.  Antifungal agents: in vitro susceptibility testing, pharmacodynamics, and prospects for combination therapy.

Authors:  A H Groll; H Kolve
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2004-03-11       Impact factor: 3.267

2.  Functional assignment of YvgO, a novel set of purified and chemically characterized proteinaceous antifungal variants produced by Bacillus thuringiensis SF361.

Authors:  David C Manns; John J Churey; Randy W Worobo
Journal:  Appl Environ Microbiol       Date:  2012-02-03       Impact factor: 4.792

3.  Identification of essential genes in the human fungal pathogen Aspergillus fumigatus by transposon mutagenesis.

Authors:  Arnaud Firon; François Villalba; Roland Beffa; Christophe D'Enfert
Journal:  Eukaryot Cell       Date:  2003-04

4.  Antifungal properties and target evaluation of three putative bacterial histidine kinase inhibitors.

Authors:  R J Deschenes; H Lin; A D Ault; J S Fassler
Journal:  Antimicrob Agents Chemother       Date:  1999-07       Impact factor: 5.191

5.  Protection of killer antiidiotypic antibodies against early invasive aspergillosis in a murine model of allogeneic T-cell-depleted bone marrow transplantation.

Authors:  Elio Cenci; Antonella Mencacci; Antonio Spreca; Claudia Montagnoli; Angela Bacci; Katia Perruccio; Andrea Velardi; Walter Magliani; Stefania Conti; Luciano Polonelli; Luigina Romani
Journal:  Infect Immun       Date:  2002-05       Impact factor: 3.441

6.  Effect of clotrimazole on the pump cycle of the Na,K-ATPase.

Authors:  Gianluca Bartolommei; Nadège Devaux; Francesco Tadini-Buoninsegni; Mariarosa Moncelli; Hans-Jürgen Apell
Journal:  Biophys J       Date:  2008-05-09       Impact factor: 4.033

7.  Effect of polygodial on the mitochondrial ATPase of Saccharomyces cerevisiae.

Authors:  C S Lunde; I Kubo
Journal:  Antimicrob Agents Chemother       Date:  2000-07       Impact factor: 5.191

8.  Antifungal effect of 4-arylthiosemicarbazides against Candida species. Search for molecular basis of antifungal activity of thiosemicarbazide derivatives.

Authors:  Agata Siwek; Joanna Stefańska; Katarzyna Dzitko; Artur Ruszczak
Journal:  J Mol Model       Date:  2012-04-26       Impact factor: 1.810

9.  Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole.

Authors:  Michaela Spitzer; Emma Griffiths; Kim M Blakely; Jan Wildenhain; Linda Ejim; Laura Rossi; Gianfranco De Pascale; Jasna Curak; Eric Brown; Mike Tyers; Gerard D Wright
Journal:  Mol Syst Biol       Date:  2011-06-21       Impact factor: 11.429

10.  The Candida Genome Database (CGD), a community resource for Candida albicans gene and protein information.

Authors:  Martha B Arnaud; Maria C Costanzo; Marek S Skrzypek; Gail Binkley; Christopher Lane; Stuart R Miyasato; Gavin Sherlock
Journal:  Nucleic Acids Res       Date:  2005-01-01       Impact factor: 16.971
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