Literature DB >> 9582008

Effect of ashwagandha on lipid peroxidation in stress-induced animals.

J N Dhuley1.   

Abstract

The aqueous suspension of root extract of an Indian drug ashwagandha (Withania somnifera L. (Solanaceae)) was evaluated for its effect on lipid peroxidation (LPO) in stress-induced animals. Elevation of LPO was observed in rabbits and mice after intravenous administration of 0.2 microg/kg of lipopolysaccharide (LPS: from Klebsiella pneumoniae) and 100 microg/kg of peptidoglycan (PGN: from Staphylococcus aureus), respectively. The peak was reached immediately after PGN and 2-6 h after LPS administration. Simultaneous oral administration of ashwagandha (100 mg/kg) prevented the rise in LPO in rabbits and mice.

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Year:  1998        PMID： 9582008     DOI： 10.1016/s0378-8741(97)00151-7

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN： 0378-8741            Impact factor:   4.360


  27 in total

1.  Neuroprotective effects of Withania somnifera dunal.: A possible mechanism.

Authors:  Maheep Bhatnagar; Durgesh Sharma; Mahendra Salvi
Journal:  Neurochem Res       Date:  2009-05-15       Impact factor: 3.996

2.  Involvement of Cholinergic and Adrenergic Receptors in Pathogenesis and Inflammatory Response Induced by Alpha-Neurotoxin Bot III of Scorpion Venom.

Authors:  Imene Nakib; Marie-France Martin-Eauclaire; Fatima Laraba-Djebari
Journal:  Inflammation       Date:  2016-10       Impact factor: 4.092

3.  Oxidative stress induced NMDA receptor alteration leads to spatial memory deficits in temporal lobe epilepsy: ameliorative effects of Withania somnifera and Withanolide A.

Authors:  Smijin Soman; P K Korah; S Jayanarayanan; Jobin Mathew; C S Paulose
Journal:  Neurochem Res       Date:  2012-06-15       Impact factor: 3.996

4.  Copper-stress induced alterations in protein profile and antioxidant enzymes activities in the in vitro grown Withania somnifera L.

Authors:  Jyoti R Rout; Shidharth S Ram; Ritarani Das; Anindita Chakraborty; Mathummal Sudarshan; Santi L Sahoo
Journal:  Physiol Mol Biol Plants       Date:  2013-07

Review 5.  Pharmacologic overview of Withania somnifera, the Indian Ginseng.

Authors:  Nawab John Dar; Abid Hamid; Muzamil Ahmad
Journal:  Cell Mol Life Sci       Date:  2015-08-26       Impact factor: 9.261

6.  Studies on the protective and immunomodulatory efficacy of Withania somnifera along with cisplatin against experimental visceral leishmaniasis.

Authors:  Heena Sachdeva; Rakesh Sehgal; Sukhbir Kaur
Journal:  Parasitol Res       Date:  2013-03-22       Impact factor: 2.289

7.  Withania somnifera root powder protects againist post-traumatic stress disorder-induced memory impairment.

Authors:  Karem H Alzoubi; Arwa S Al Hilo; Qosay A Al-Balas; Khalid El-Salem; Tamam El-Elimat; Feras Q Alali
Journal:  Mol Biol Rep       Date:  2019-06-19       Impact factor: 2.316

8.  Ayurvedic Balarista ameliorate anti-arthritic activity in adjuvant induced arthritic rats by inhibiting pro-inflammatory cytokines and oxidative stress.

Authors:  C Das; A Bose; D Das
Journal:  J Tradit Complement Med       Date:  2020-05-04

9.  Naturopathic care for anxiety: a randomized controlled trial ISRCTN78958974.

Authors:  Kieran Cooley; Orest Szczurko; Dan Perri; Edward J Mills; Bob Bernhardt; Qi Zhou; Dugald Seely
Journal:  PLoS One       Date:  2009-08-31       Impact factor: 3.240

10.  Critical evaluation of ayurvedic plants for stimulating intrinsic antioxidant response.

Authors:  Sunil Dutt Shukla; Maheep Bhatnagar; Sukant Khurana
Journal:  Front Neurosci       Date:  2012-07-26       Impact factor: 4.677
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