| Literature DB >> 9580945 |
Abstract
Immune cells of myeloid and lymphoid lineages constitute a significant cell mass in the corpus luteum. Changes in the distribution and numbers of these cells within the corpus luteum take place during the life span of the corpus luteum. These cells are now recognized to be important both in structural changes of the corpus luteum as well as in the regulation of steroidogenesis. Cytokines are secreted from immune cells and other cells of the corpus luteum and comprise an important component of the intercellular signaling that is regulating tissue remodeling and the endocrine activity of the gland. This review covers recent findings of the participation of immune cells and cytokines in the regulation of the corpus luteum function.Mesh:
Substances:
Year: 1997 PMID: 9580945 DOI: 10.1055/s-2008-1068374
Source DB: PubMed Journal: Semin Reprod Endocrinol ISSN: 0734-8630