Literature DB >> 9580122

Synthesis and in vitro anthelmintic activity against Nippostrongylus brasiliensis of new 2-amino-4-hydroxy-delta-valerolactam derivatives.

S Gordon1, L Costa, M Incerti, E Manta, J Saldaña, L Domínguez, R Mariezcurrena, L Suescun.   

Abstract

The synthesis of a series of 2-amino-4-hydroxy-delta-valerolactam derivatives is described (compounds 4 to 10). These compounds showed a high anthelmintic in vitro activity against the Nippostrongylus brasiliensis model.

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Year:  1997        PMID: 9580122

Source DB:  PubMed          Journal:  Farmaco        ISSN: 0014-827X


  2 in total

1.  Use of L4 larvae of Nippostrongylus brasiliensis for the in vivo screening of anthelmintic drugs.

Authors:  L Domínguez; J Saldaña; J Chernin
Journal:  Can J Vet Res       Date:  2000-07       Impact factor: 1.310

2.  Synthesis of bicyclic 1,4-thiazepines as novel anti-Trypanosoma brucei brucei agents.

Authors:  Franco Vairoletti; Andrea Medeiros; Pablo Fontán; Jennifer Meléndrez; Carlos Tabárez; Gustavo Salinas; Jaime Franco; Marcelo A Comini; Jenny Saldaña; Vojtech Jancik; Graciela Mahler; Cecilia Saiz
Journal:  Medchemcomm       Date:  2019-06-11       Impact factor: 3.597

  2 in total

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