Literature DB >> 9579858

Human gene therapy.

W F Anderson1.   

Abstract

Although gene therapy as a treatment for disease holds great promise, progress in developing effective clinical protocols has been slow. The problem lies in the development of safe and efficient gene-delivery systems. This review will evaluate the problems and the potential solutions in this new field of medicine.

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Mesh：

Year:  1998        PMID： 9579858     DOI： 10.1038/32058

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  107 in total

1.  Nonmyeloablative immunosuppressive regimen prolongs In vivo persistence of gene-modified autologous T cells in a nonhuman primate model.

Authors:  C Berger; M L Huang; M Gough; P D Greenberg; S R Riddell; H P Kiem
Journal:  J Virol       Date:  2001-01       Impact factor: 5.103

Review 2.  Herpes simplex virus vectors for gene therapy in Parkinson's disease and other diseases of the nervous system.

Authors:  D S Latchman
Journal:  J R Soc Med       Date:  1999-11       Impact factor: 5.344

Review 3.  Gene delivery from replication-selective viruses: arming guided missiles in the war against cancer.

Authors:  T Hermiston
Journal:  J Clin Invest       Date:  2000-05       Impact factor: 14.808

4.  Ophthalmology in the post-genomic era.

Authors:  G C Black; M E Boulton; P N Bishop; D McLeod
Journal:  Br J Ophthalmol       Date:  1999-11       Impact factor: 4.638

Review 5.  Molecular therapy in ocular wound healing.

Authors:  M F Cordeiro; G S Schultz; R R Ali; S S Bhattacharya; P T Khaw
Journal:  Br J Ophthalmol       Date:  1999-11       Impact factor: 4.638

6.  Identification of the block in targeted retroviral-mediated gene transfer.

Authors:  Y Zhao; L Zhu; S Lee; L Li; E Chang; N W Soong; D Douer; W F Anderson
Journal:  Proc Natl Acad Sci U S A       Date:  1999-03-30       Impact factor: 11.205

7.  Systemic administration of TerplexDNA system: pharmacokinetics and gene expression.

Authors:  L Yu; H Suh; J J Koh; S W Kim
Journal:  Pharm Res       Date:  2001-09       Impact factor: 4.200

8.  Gene therapy: new "magic bullets" to prevent ocular scarring.

Authors:  P T Khaw; A D Cambrey; G A Limb; J T Daniels
Journal:  Br J Ophthalmol       Date:  2002-05       Impact factor: 4.638

9.  A new hybrid system capable of efficient lentiviral vector production and stable gene transfer mediated by a single helper-dependent adenoviral vector.

Authors:  Shuji Kubo; Kohnosuke Mitani
Journal:  J Virol       Date:  2003-03       Impact factor: 5.103

10.  Gene transfer in vitro and in vivo by cationic lipids is not significantly affected by levels of supercoiling of a reporter plasmid.

Authors:  D Bergan; T Galbraith; D L Sloane
Journal:  Pharm Res       Date:  2000-08       Impact factor: 4.200
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