Literature DB >> 9578321

Molecular markers of carcinogenesis.

P W Brandt-Rauf1, M R Pincus.   

Abstract

The protein products of oncogenes and tumor suppressor genes play critical roles in the development of many cancers. The expression of a number of these proteins can be detected in extracellular fluids such as blood. This article reviews the literature on the application of methods for the detection of the proteins of oncogenes and tumor suppressor genes in the blood of humans with cancer or at risk for the development of cancer. The detection of these proteins in blood may be useful molecular markers of carcinogenesis that could play an important part in cancer diagnosis, prognosis, and prevention.

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Year:  1998        PMID： 9578321     DOI： 10.1016/s0163-7258(97)00111-3

Source DB:  PubMed          Journal:  Pharmacol Ther        ISSN： 0163-7258            Impact factor:   12.310


  2 in total

1.  Differences in tumor-associated protein levels among middle-age Flemish women in association with area of residence and exposure to pollutants.

Authors:  Nicolas A van Larebeke; Marc E Bracke; Vera Nelen; Gudrun Koppen; Greet Schoeters; Herman Van Loon; Robert Vlietinck
Journal:  Environ Health Perspect       Date:  2006-06       Impact factor: 9.031

2.  Pollutant effects on genotoxic parameters and tumor-associated protein levels in adults: a cross sectional study.

Authors:  Sam De Coster; Gudrun Koppen; Marc Bracke; Carmen Schroijen; Elly Den Hond; Vera Nelen; Els Van de Mieroop; Liesbeth Bruckers; Maaike Bilau; Willy Baeyens; Greet Schoeters; Nik van Larebeke
Journal:  Environ Health       Date:  2008-06-03       Impact factor: 5.984
  2 in total

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