Literature DB >> 9578284

Hydatidiform mole with non-metastatic pulmonary complications and a false low level of hCG.

F Flam1, K Hambraeus-Jonzon, L O Hansson, A Kjaeldgaard.   

Abstract

We present a case of hydatidiform mole with non-metastatic pulmonary complications and stress that termination of the pregnancy will cure the patient. The frequent use of sonography in early pregnancy makes it possible to diagnose pathological pregnancies earlier than was possible before. The fact that molar pregnancies are now being terminated at an earlier stage means that some of the complications associated with advanced moles are seldom encountered today. The case also illustrates the so-called 'high dose hook effect' meaning that an extremely high level of hCG may falsely be reported to be very low by the laboratory.

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Year:  1998        PMID: 9578284     DOI: 10.1016/s0301-2115(97)00268-6

Source DB:  PubMed          Journal:  Eur J Obstet Gynecol Reprod Biol        ISSN: 0301-2115            Impact factor:   2.435


  3 in total

Review 1.  New discoveries on the biology and detection of human chorionic gonadotropin.

Authors:  Laurence A Cole
Journal:  Reprod Biol Endocrinol       Date:  2009-01-26       Impact factor: 5.211

2.  A giant ovarian cyst in a neonate with classical 21-hydroxylase deficiency with very high testosterone levels demonstrating a high-dose hook effect.

Authors:  Tülay Güran; Gözde Yeşil; Ömer Güran; Suna Cesur; Oktav Bosnalı; Ayşenur Celayir; Sevilay Topçuoğlu; Abdullah Bereket
Journal:  J Clin Res Pediatr Endocrinol       Date:  2012-05-02

3.  Molar Pregnancy with False Negative β-hCG Urine in the Emergency Department.

Authors:  Christopher L Hunter; Jay Ladde
Journal:  West J Emerg Med       Date:  2011-05
  3 in total

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