Retrograde double-labeling study of retinal ganglion cells from the ipsilateral vLGN and SC in the albino rat.

Retinal ganglion cells with branches to the ipsilateral ventral lateral geniculate nucleus (vLGN) and superior colliculus (SC) were studied by retrograde fluorescent double-labeling. Double-labeled cells were found in the ventral temporal crescent of the retina, with a few ipsilaterally projecting single-labeled cells scattered in this area. Single-labeled vLGN-projecting cells were found predominantly in the ventral-temporal crescent and to a lesser extent in the temporal and dorsotemporal octant. SC-projecting cells were present predominantly in the ventral-temporal crescent and to a lesser extent in the ventral and ventronasal octant. Our best animal model had 2200 ipsilaterally labeled cells. There were 451 (20.5%) double-labeled vLGN and SC-projecting cells, 561 (25.5%) single-labeled vLGN-projecting cells, and 1186 (53.9%) single-labeled SC-projecting cells.