Literature DB >> 9573494

Subgingival controlled release of antimicrobial agents in the treatment of periodontal disease.

G L Southard1, K C Godowski.   

Abstract

Local drug delivery of antimicrobics by sustained release delivery systems can be used to treat periodontal disease. Advantages of these systems may include biodegradation of the system, maintaining high levels of antibiotic in the gingival crevicular fluid (GCF) for a sustained period of time and ease of use with high patient acceptance. This review will identify human in vivo clinical and microbiological studies. Sustained release formulations, application methods, clinical results and microbiological effects are discussed.

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Year:  1998        PMID： 9573494     DOI： 10.1016/s0924-8579(98)00004-1

Source DB:  PubMed          Journal:  Int J Antimicrob Agents        ISSN： 0924-8579            Impact factor:   5.283


  7 in total

1.  Inhibition of the activities of matrix metalloproteinases 2, 8, and 9 by chlorhexidine.

Authors:  R Gendron; D Grenier; T Sorsa; D Mayrand
Journal:  Clin Diagn Lab Immunol       Date:  1999-05

2.  Drug-loaded polymeric composite skin graft for infection-free wound healing: fabrication, characterization, cell proliferation, migration, and antimicrobial activity.

Authors:  Anupama Mittal; Neeraj Kumar
Journal:  Pharm Res       Date:  2012-06-28       Impact factor: 4.200

3.  A novel injectable chlorhexidine thermosensitive hydrogel for periodontal application: preparation, antibacterial activity and toxicity evaluation.

Authors:  Qiu Xia Ji; Qing Sheng Zhao; Jing Deng; Rui Lü
Journal:  J Mater Sci Mater Med       Date:  2010-05-26       Impact factor: 3.896

4.  Aggregatibacter actinomycetemcomitans biofilm killing by a targeted ciprofloxacin prodrug.

Authors:  Benjamin D Reeves; Mark Young; Paul A Grieco; Peter Suci
Journal:  Biofouling       Date:  2013-08-19       Impact factor: 3.209

5.  Electrospun PLA Fibers Containing Metronidazole for Periodontal Disease.

Authors:  Mária Budai-Szűcs; Attila Léber; Lu Cui; Muriel Józó; Péter Vályi; Katalin Burián; Balázs Kirschweng; Erzsébet Csányi; Béla Pukánszky
Journal:  Drug Des Devel Ther       Date:  2020-01-16       Impact factor: 4.162

6.  Thermosensitive periodontal sol of ciprofloxacin hydrochloride and serratiopeptidase: Pharmaceutical and mechanical analysis.

Authors:  Kushal Pal Singh; Gulshan Chhabra; Vijay Sharma; Kamla Pathak
Journal:  Int J Pharm Investig       Date:  2014-01

7.  Peptide KSL-W-Loaded Mucoadhesive Liquid Crystalline Vehicle as an Alternative Treatment for Multispecies Oral Biofilm.

Authors:  Jéssica Bernegossi; Giovana Maria Fioramonti Calixto; Paulo Ricardo da Silva Sanches; Carla Raquel Fontana; Eduardo Maffud Cilli; Saulo Santesso Garrido; Marlus Chorilli
Journal:  Molecules       Date:  2015-12-25       Impact factor: 4.411
  7 in total

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