Literature DB >> 9573133

Lipoprotein(a) inhibits lipopolysaccharide-induced tumor necrosis factor alpha production by human mononuclear cells.

M G Netea1, N de Bont, P N Demacker, B J Kullberg, L E Jacobs, T J Verver-Jansen, A F Stalenhoef, J W Van der Meer.   

Abstract

Lipoproteins can bind lipopolysaccharide (LPS) and decrease LPS-stimulated cytokine production. Lipoprotein(a) [Lp(a)] was as potent as low-density lipoproteins (LDL) in inhibiting LPS-stimulated tumor necrosis factor synthesis by human mononuclear cells. The kinetics of LPS inhibition by Lp(a) was similar to that of LDL. This suggests that circulating Lp(a) may be an important factor determining the amplitude of the response to LPS in humans.

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Year:  1998        PMID： 9573133      PMCID： PMC108207          DOI： 10.1128/IAI.66.5.2365-2367.1998

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  24 in total

1.  The variation of serum lipoprotein (a) during surgical operations.

Authors:  B Magnani; P P Massone; F Meriggi; F di Jeso
Journal:  Clin Chim Acta       Date:  1992-11-30       Impact factor: 3.786

2.  Correlation between endotoxin-neutralizing capacity of human plasma as tested by the limulus-amebocyte-lysate-test and plasma protein levels.

Authors:  D Berger; S Schleich; M Seidelmann; H G Beger
Journal:  FEBS Lett       Date:  1990-12-17       Impact factor: 4.124

3.  Evaluation of the dual-precipitation method by comparison with the ultracentrifugation method for measurement of lipoproteins in serum.

Authors:  P N Demacker; H E Vos-Janssen; A P Jansen; A van 't Laar
Journal:  Clin Chem       Date:  1977-07       Impact factor: 8.327

4.  Antiinflammatory effects of reconstituted high-density lipoprotein during human endotoxemia.

Authors:  D Pajkrt; J E Doran; F Koster; P G Lerch; B Arnet; T van der Poll; J W ten Cate; S J van Deventer
Journal:  J Exp Med       Date:  1996-11-01       Impact factor: 14.307

5.  Human very low density lipoproteins and chylomicrons can protect against endotoxin-induced death in mice.

Authors:  H W Harris; C Grunfeld; K R Feingold; J H Rapp
Journal:  J Clin Invest       Date:  1990-09       Impact factor: 14.808

Review 6.  Lipoprotein(a). A genetic risk factor for premature coronary heart disease.

Authors:  A M Scanu
Journal:  JAMA       Date:  1992-06-24       Impact factor: 56.272

7.  The role of lipoproteins and receptor-mediated endocytosis in the transport of bacterial lipopolysaccharide.

Authors:  B J Van Lenten; A M Fogelman; M E Haberland; P A Edwards
Journal:  Proc Natl Acad Sci U S A       Date:  1986-04       Impact factor: 11.205

Review 8.  Adjunctive therapy for septic shock: a review of experimental approaches.

Authors:  W A Lynn; J Cohen
Journal:  Clin Infect Dis       Date:  1995-01       Impact factor: 9.079

9.  In vitro inactivation of bacterial endotoxin by human lipoproteins and apolipoproteins.

Authors:  K Emancipator; G Csako; R J Elin
Journal:  Infect Immun       Date:  1992-02       Impact factor: 3.441

10.  Plasma endotoxin as a predictor of multiple organ failure and death in systemic meningococcal disease.

Authors:  P Brandtzaeg; P Kierulf; P Gaustad; A Skulberg; J N Bruun; S Halvorsen; E Sørensen
Journal:  J Infect Dis       Date:  1989-02       Impact factor: 5.226
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  6 in total

1.  Low density lipoprotein inactivates Vibrio vulnificus cytolysin through the oligomerization of toxin monomer.

Authors:  Kwang-Hyun Park; Haet-Bit Yang; Hyung-Gue Kim; Young-Rae Lee; Hyoun Hur; Jong-Soo Kim; Bon-Sun Koo; Myung-Kwan Han; Jong-Hyun Kim; Young-Ju Jeong; Jong-Suk Kim
Journal:  Med Microbiol Immunol       Date:  2004-11-20       Impact factor: 3.402

2.  Apolipoprotein(a) inhibits lipopolysaccharide-induced IL-6 secretion in human astrocytoma cell line by interfering with lipopolysaccharide signaling.

Authors:  Guglielmina Chimienti; Anna Mezzapesa; Grazia M Liuzzi; Tiziana Latronico; Gabriella Pepe
Journal:  Inflamm Res       Date:  2010-11-02       Impact factor: 4.575

3.  Haptoglobin dampens endotoxin-induced inflammatory effects both in vitro and in vivo.

Authors:  Mohamed S Arredouani; Ahmad Kasran; Jeroen A Vanoirbeek; Frank G Berger; Heinz Baumann; Jan L Ceuppens
Journal:  Immunology       Date:  2005-02       Impact factor: 7.397

4.  Heart failure and statins--why do we need a clinical trial?

Authors:  M Böhm; A Hjalmarson; J Kjekshus; U Laufs; J McMurray; D J van Veldhuisen
Journal:  Z Kardiol       Date:  2005-04

Review 5.  Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock.

Authors:  Edwin S Van Amersfoort; Theo J C Van Berkel; Johan Kuiper
Journal:  Clin Microbiol Rev       Date:  2003-07       Impact factor: 26.132

6.  Hyperlipidemia impaired innate immune response to periodontal pathogen porphyromonas gingivalis in apolipoprotein E knockout mice.

Authors:  Lang Lei; Houxuan Li; Fuhua Yan; Yin Xiao
Journal:  PLoS One       Date:  2013-08-16       Impact factor: 3.240
  6 in total

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