OBJECTIVES: To review the literature about common autoantibodies produced in association with viral infection. METHODS: Medline review of the medical literature published in English. RESULTS: Common viral infections are often associated with low-titer, polyspecific autoantibodies. However, high-titer antinuclear antibodies, double-stranded DNA antibodies, anticardiolipin antibodies, and other subtype antibodies may be found. Hepatitis C and B virus, human immunodeficiency virus, and parvovirus B19 appear to be associated with autoantibodies more commonly than other viruses. CONCLUSIONS: Transient autoantibodies resulting from viral infections are not uncommon. Clinical and laboratory follow-up over time will help distinguish between connective tissue disease and self-limited illness.
OBJECTIVES: To review the literature about common autoantibodies produced in association with viral infection. METHODS: Medline review of the medical literature published in English. RESULTS: Common viral infections are often associated with low-titer, polyspecific autoantibodies. However, high-titer antinuclear antibodies, double-stranded DNA antibodies, anticardiolipin antibodies, and other subtype antibodies may be found. Hepatitis C and B virus, human immunodeficiency virus, and parvovirus B19 appear to be associated with autoantibodies more commonly than other viruses. CONCLUSIONS: Transient autoantibodies resulting from viral infections are not uncommon. Clinical and laboratory follow-up over time will help distinguish between connective tissue disease and self-limited illness.
Authors: Gregg E Dinse; Christine G Parks; Helen C S Meier; Caroll A Co; Edward K L Chan; Todd A Jusko; James Yeh; Frederick W Miller Journal: J Autoimmun Date: 2018-05-18 Impact factor: 7.094
Authors: Els De Schryver; Lien Calus; Henryk Bonte; De Ruyck Natalie; Hannah Gould; Erin Donovan; Dirk Elewaut; Rudolf Valenta; Irene Mittermann; Jan Gutermuth; Tanja Seher; Robert P Schleimer; Bruce K Tan; Lara Derycke; Thibaut Van Zele; Claus Bachert; Philippe Gevaert Journal: J Allergy Clin Immunol Date: 2016-05-06 Impact factor: 10.793