Literature DB >> 9572680

Mycobacterium leprae binds to a 25-kDa phosphorylated glycoprotein of human peripheral nerve.

L M Suneetha1, P R Satish, R J Korula, S K Suneetha, C K Job, A S Balasubramanian.   

Abstract

Mycobacterium leprae, the causative agent of leprosy, specifically invades and destroys the peripheral nerve, which results in the main clinical manifestation of the disease. Little is known about the bacteria-nerve protein interaction. We show in the present work that M leprae binds to a 25 kDa glycoprotein from human peripheral nerve. This protein is phosphorylatable and it binds to lectins which have alpha-mannose specificity. This M leprae-protein interaction could be of importance in the pathogenesis of leprosy.

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Year:  1998        PMID： 9572680     DOI： 10.1023/a:1022471331168

Source DB:  PubMed          Journal:  Neurochem Res        ISSN： 0364-3190            Impact factor:   3.996


  30 in total

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Journal:  Neuron       Date:  1991-11       Impact factor: 17.173

Review 2.  Phosphorylation of myelin protein: recent advances.

Authors:  J Eichberg; S Iyer
Journal:  Neurochem Res       Date:  1996-04       Impact factor: 3.996

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Journal:  J Clin Invest       Date:  1990-04       Impact factor: 14.808

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Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

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Authors:  R C Wiggins; P Morell
Journal:  J Neurochem       Date:  1980-03       Impact factor: 5.372

7.  Interaction of enteropathogenic Yersinia enterocolitica with complex basement membranes and the extracellular matrix proteins collagen type IV, laminin-1 and -2, and nidogen/entactin.

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Journal:  J Biol Chem       Date:  1994-11-25       Impact factor: 5.157

8.  Protein phosphorylation in human peripheral nerve: altered phosphorylation of a 25-kDa glycoprotein in leprosy.

Authors:  L M Suneetha; R J Korula; A S Balasubramanian
Journal:  Neurochem Res       Date:  1996-06       Impact factor: 3.996

9.  Analysis of saccharide binding to Artocarpus integrifolia lectin reveals specific recognition of T-antigen (beta-D-Gal(1----3)D-GalNAc).

Authors:  M V Sastry; P Banarjee; S R Patanjali; M J Swamy; G V Swarnalatha; A Surolia
Journal:  J Biol Chem       Date:  1986-09-05       Impact factor: 5.157

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Authors:  S Hilmi; M Fournier; H Valeins; J C Gandar; J Bonnet
Journal:  J Neurochem       Date:  1995-02       Impact factor: 5.372
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  1 in total

1.  Mycobacterium leprae binds to a major human peripheral nerve glycoprotein myelin P zero (P0).

Authors:  Lavanya M Suneetha; Surya S Singh; Meher Vani; Deena Vardhini; David Scollard; Juan J Archelos; M Srinivasulu; Sujai Suneetha
Journal:  Neurochem Res       Date:  2003-09       Impact factor: 3.996
  1 in total

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