J L Powell1, R D McAfee, R C McCoy, B S Shiro. 1. Department of Obstetrics and Gynecology, Coastal Area Health Education Center, New Hanover Regional Medical Center, Wilmington, North Carolina 28402-9025, USA.
Abstract
BACKGROUND: The decision to recommend removal or conservation of a normal ovary and uterus in a young woman with advanced ovarian cancer is difficult and controversial. CASE: A 21-year-old patient with a large-cell variant of small-cell carcinoma of the ovary stage IIIc underwent optimal debulking surgery with preservation of the normal appearing uterus and opposite adnexa followed by aggressive multi-agent chemotherapy. She is menstruating normally and is free of disease, more than 2 years since completion of chemotherapy. CONCLUSION: In selected cases, conservation of the uninvolved ovary and uterus in patients with advanced-stage, small-cell carcinoma of the ovary may not compromise survival.
BACKGROUND: The decision to recommend removal or conservation of a normal ovary and uterus in a young woman with advanced ovarian cancer is difficult and controversial. CASE: A 21-year-old patient with a large-cell variant of small-cell carcinoma of the ovary stage IIIc underwent optimal debulking surgery with preservation of the normal appearing uterus and opposite adnexa followed by aggressive multi-agent chemotherapy. She is menstruating normally and is free of disease, more than 2 years since completion of chemotherapy. CONCLUSION: In selected cases, conservation of the uninvolved ovary and uterus in patients with advanced-stage, small-cell carcinoma of the ovary may not compromise survival.
Authors: Lisa F Gamwell; Karen Gambaro; Maria Merziotis; Colleen Crane; Suzanna L Arcand; Valerie Bourada; Christopher Davis; Jeremy A Squire; David G Huntsman; Patricia N Tonin; Barbara C Vanderhyden Journal: Orphanet J Rare Dis Date: 2013-02-21 Impact factor: 4.123