BACKGROUND: The histologic classification of epithelial salivary gland tumors may present difficulties due to their great morphologic diversity. METHODS: In this study, 478 parotid gland tumors were reevaluated and reclassified according to the 1991 WHO histologic classification of salivary gland tumors. RESULTS: In 56 cases, the original diagnosis was changed, either within the benign or the malignant tumor group. In six cases (1.3%), the original diagnosis was changed from benign to malignant or vice versa. CONCLUSIONS: During the mean follow-up period of 10.3 years, no events occurred supporting or rejecting the proposed change in diagnosis in these six patients. With regard to the three cases in which an original malignant diagnosis was made, the possibility of an overdiagnosis, and therefore an overtreatment, remains.
BACKGROUND: The histologic classification of epithelial salivary gland tumors may present difficulties due to their great morphologic diversity. METHODS: In this study, 478 parotid gland tumors were reevaluated and reclassified according to the 1991 WHO histologic classification of salivary gland tumors. RESULTS: In 56 cases, the original diagnosis was changed, either within the benign or the malignant tumor group. In six cases (1.3%), the original diagnosis was changed from benign to malignant or vice versa. CONCLUSIONS: During the mean follow-up period of 10.3 years, no events occurred supporting or rejecting the proposed change in diagnosis in these six patients. With regard to the three cases in which an original malignant diagnosis was made, the possibility of an overdiagnosis, and therefore an overtreatment, remains.
Authors: Lester D R Thompson; Justin L Bauer; Simion Chiosea; Jonathan B McHugh; Raja R Seethala; Markku Miettinen; Susan Müller Journal: Head Neck Pathol Date: 2014-08-21
Authors: Fabrizio Grandi; Marcia M Colodel; Lidianne N Monteiro; João Rafael V P Leão; Noeme S Rocha Journal: BMC Vet Res Date: 2010-09-16 Impact factor: 2.741