Literature DB >> 9570615

Sympathetic hyperactivity, respiratory failure, pruritus, and anesthesia after unintentional epidural injection of potassium chloride: case report.

P do Nascimento1, N S Módolo, J F Meletti, J R Braz.   

Abstract

BACKGROUND AND OBJECTIVES: A combination of epidural and general anesthesia has been widely used to attenuate the surgical stress response and to provide postoperative analgesia. This case report illustrates the use of this anesthetic technique. Analgesia was induced with local anesthetic in the immediate postoperative period using unintentional 19.1% potassium chloride (KCl) as diluent.
METHODS: An ASA I male patient was scheduled for surgical correction of idiopathic megaesophagus under continuous epidural anesthesia combined with general anesthesia. In the postoperative period, while preparing 10 mL 0.125% bupivacaine to be administered through the epidural catheter for pain control, 5 mL 19.1% KCl was unintentionally used as diluent, resulting in a 9.55% potassium solution concentration.
RESULTS: The patient developed warmness of the lower limbs, tachycardia, hypertension, intense pruritus on the chest, agitation, exacerbation of sensory and motor blocks, and respiratory failure secondary to pulmonary edema, requiring ventilatory support. Total recovery was observed after 24 hours.
CONCLUSIONS: Epidurally injected potassium leads to severe clinical manifestations caused by autonomic dysfunction, spinal cord irritation, and possible release of histamine. Despite continuous recommendations, ampule misidentification still happens in hospitals, frequently leading to serious accidents.

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Year:  1998        PMID: 9570615     DOI: 10.1097/00115550-199823020-00019

Source DB:  PubMed          Journal:  Reg Anesth Pain Med        ISSN: 1098-7339            Impact factor:   6.288


  4 in total

1.  [Brachial plexus. Anesthesia and analgesia].

Authors:  S Schulz-Stübner
Journal:  Anaesthesist       Date:  2003-06-18       Impact factor: 1.041

2.  Inadvertent injection of potassium chloride instead of sodium chloride during treatment of chronic low back ache with epidural injection leading to paraplegia.

Authors:  Rahul Ranjan; Naiyer Asif; Sohail Ahmad; Syed Ifthekar
Journal:  J Craniovertebr Junction Spine       Date:  2016 Oct-Dec

3.  Inadvertent injection of piperacillin - tazobactum into epidural space.

Authors:  Apurva Agarwal; Sameer Goyal; Anil Kr Verma; Shaily Agarwal
Journal:  J Anaesthesiol Clin Pharmacol       Date:  2010-10

4.  Inadvertent administration of potassium chloride in the epidural space: How to prevent the inevitable.

Authors:  Jasmeet Kaur; Adarsh C Swami; Ashwini Sharma; Kanika Arora
Journal:  J Anaesthesiol Clin Pharmacol       Date:  2019 Jan-Mar
  4 in total

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