Literature DB >> 9570237

High prevalence of hepatitis G virus infection in multiply transfused children with thalassaemia.

Y Poovorawan1, A Theamboonlers, V Chongsrisawat, P Seksarn, L Jarvis, P Simmonds.   

Abstract

We investigated the prevalence of hepatitis G virus (HGV) RNA in relation to the frequency of blood transfusions in thalassaemic children and in volunteer blood donors in Thailand. Furthermore, we studied the frequency of coinfection with hepatitis B virus (HBV) and/or hepatitis C virus (HCV) as well as a possible relationship to the alanine aminotransferase (ALT) status of the blood samples, taken at random from thalassaemic children who have received multiple blood transfusions and from volunteer blood donors. The results show detectable HGV-RNA in 32.6% of transfusion patients and in 5% of blood donors. The prevalence of HGV-RNA peaked between the 11th and 50th transfusion. The relationship between HGV infection and ALT status was not statistically relevant.

Entities:  

Keywords:  Age Factors; Asia; Blood Donors; Blood Supply; Blood Transfusion; Child; Clinical Research; Comparative Studies; Demographic Factors; Developing Countries; Diseases; Equipment And Supplies; Hepatitis; Measurement; Population; Population Characteristics; Prevalence; Research Methodology; Research Report; Southeastern Asia; Studies; Thailand; Treatment; Viral Diseases; Youth

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Year:  1998        PMID: 9570237     DOI: 10.1111/j.1440-1746.1998.01552.x

Source DB:  PubMed          Journal:  J Gastroenterol Hepatol        ISSN: 0815-9319            Impact factor:   4.029


  2 in total

1.  Hepatitis TT virus infection in high-risk groups.

Authors:  Y Poovorawan; A Theamboonlers; P Jantaradsamee; N Kaew-in; P Hirsch; P Tangkitvanich
Journal:  Infection       Date:  1998 Nov-Dec       Impact factor: 3.553

2.  Local Virus Extinctions following a Host Population Bottleneck.

Authors:  Beatrix Kapusinszky; Usha Mulvaney; Anna J Jasinska; Xutao Deng; Nelson Freimer; Eric Delwart
Journal:  J Virol       Date:  2015-05-27       Impact factor: 5.103

  2 in total

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