Literature DB >> 956813

Influence of age and time interval between death and autopsy on dopamine and 3-methoxytyramine levels in human basal ganglia.

A Carlsson, B Winblad.   

Abstract

The caudate nuclei and putamens of 30 human brains were analyzed for dopamine and its metabolite 3-methoxytyramine, most of which was presumably formed from dopamine postmortally. It was found that dopamine and the sum (dopamine + methoxytyramine) but not methoxytyramine declined with the time interval between death and autopsy as well as with age.

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Year:  1976        PMID： 956813     DOI： 10.1007/BF01249444

Source DB:  PubMed          Journal:  J Neural Transm            Impact factor:   3.575


  7 in total

1.  Individual elution of noradrenaline (together with adrenaline), dopamine, 5-hydroxytryptamine and histamine from a single, strong cation exchange column, by means of mineral acid-organic solvent mixtures.

Authors:  C V Atack; T Magnusson
Journal:  J Pharm Pharmacol       Date:  1970-08       Impact factor: 3.765

2.  A method for the isolation and determination of 3-methoxytyramine in brain tissue.

Authors:  W Kehr
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1974       Impact factor: 3.000

3.  Postmortal accumulation of 3-methoxytyramine in brain.

Authors:  A Carlsson; M Lindqvist; W Kehr
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1974       Impact factor: 3.000

4.  Catecholamine metabolism in the brains of ageing male mice.

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Journal:  Brain Res       Date:  1973-03-30       Impact factor: 3.252

5.  The determination of dopamine by a modification of the dihydroxyindole fluorimetric assay.

Authors:  C V Atack
Journal:  Br J Pharmacol       Date:  1973-08       Impact factor: 8.739

6.  Monoamines in the human neostriatum: topographic distribution in normals and in Parkinson's disease and their role in akinesia, rigidity, chorea, and tremor.

Authors:  S Fahn; L R Libsch; R W Cutler
Journal:  J Neurol Sci       Date:  1971-12       Impact factor: 3.181

7.  Distribution of tyrosine hydroxylase in human and animal brain.

Authors:  E G McGeer; P L McGeer; J A Wada
Journal:  J Neurochem       Date:  1971-09       Impact factor: 5.372
  7 in total
  40 in total

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8.  Human immunodeficiency virus type 1 in the central nervous system leads to decreased dopamine in different regions of postmortem human brains.

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Review 10.  Monoamine neurons in aging and Alzheimer's disease.

Authors:  A M Palmer; S T DeKosky
Journal:  J Neural Transm Gen Sect       Date:  1993
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